A study published in the January 17, 2006, issue of the Journal of the
American College of Cardiology reported that approximately one out of
three patients hospitalized with heart failure have deficient levels of
thiamin, also known as vitamin B1. Thiamin deficiency manifests as
symptoms of congestive heart failure and, therefore, may worsen
existing heart failure. Congestive heart failure patients may be at
increased risk for thiamin deficiency as a result of diuretic-induced
urine thiamin excretion, disease severity, malnutrition, and advanced
age. Researchers measured thiamin levels among 100 heart failure
patients and compared them with measurements of 50 healthy subjects.
They found a deficiency of the vitamin in 33 percent of the heart
failure patients compared to 12 percent of those without the disease.
It has been observed that heart failure may increase the body's need
for certain nutrients, so that even individuals with healthful diets
may still come up short on vitamin B1. Researchers noted that a
relatively small dose of thiamin from a multivitamin was protective
against developing thiamin deficiency and may decrease disease severity
in those with congestive heart failure. J Am Coll Cardiol, 2006;
47:354-361
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