I have read most of the material included in the PDR regarding the
pharmacology of various 'statin' drugs in blocking the synthesis of
cholesterol in the liver. I have also read that these drugs lower the serum
C Reactive Protein, a marker for CAD. Is the mode of this reduction of CRP
an inhibition of the synthesis of CRP in the liver or is it a peripheral
blockage similar to NSAIDs on platelet adhesion etc.?
John Shamblin
General fitness, health and nutrition · Public discussion
mechanism of 'statin' drugs on CRP
This thread is locked and is currently read-only.
Thread details
What we know about this thread
- Original section
- General fitness, health and nutrition
- Published
- 31 July 2003
- Last activity
- 31 July 2003
- Original author
- John L. Shamblin, Jr.
- Posts
- 2
- Discussion status
- Public discussion
- Total views
- 291
- Views / 30 days
- 0
The navigation and discussion metadata provide context. Posts remain in their original chronological order.
-
-
"John L. Shamblin, Jr." <[email hidden]> wrote in message news:<[email hidden]>...
Quoted message said:
I have read most of the material included in the PDR regarding the
pharmacology of various 'statin' drugs in blocking the synthesis of
cholesterol in the liver. I have also read that these drugs lower the serum
C Reactive Protein, a marker for CAD. Is the mode of this reduction of CRP
an inhibition of the synthesis of CRP in the liver or is it a peripheral
blockage similar to NSAIDs on platelet adhesion etc.?
John ShamblinBecause the reduction in CRP also happens with dietary changes that
lower cholesterol, the mechanism is likely linked to the
pro-inflammatory effects of high levels of LDL (specifically oxidized
LDL).--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
http://www.heartmdphd.com/
Active in the last 60 minutes
Active in this thread
0 users · 0 guests ·0 bots ·0 total
No signed-in users are active right now.
No known search crawlers active right now.