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Hypogonadism and iron excess

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General fitness, health and nutrition
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27 May 2007
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26 June 2007
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  1. Presse Med. 2007 May 22; [Epub ahead of print][Endocrine consequences
    of hemochromatosis.][Article in French]
    Young J.
    Service d'endocrinologie et des maladies de la reproduction, CHU de
    Bicetre, Universite Paris Sud 11, Le Kremlin-Bicetre (94).

    The two most frequent endocrine complications of hemochromatosis are
    diabetes mellitus and hypogonadotrophic hypogonadism. Other endocrine
    disorders related to this disease are very rare and are described
    especially in the most severe and earliest posttransfusion iron
    overloads. Endocrine complications are evidence of advanced
    hemochromatosis, often already associated with cirrhosis. Given the
    low frequency of HFE mutations in type 2 diabetes, routine genetic
    testing in this population does not seem reasonable. Testing for iron
    overload is recommended in subjects with atypical type 2 diabetes (for
    example, patients who are not overweight) and in cases of
    hypogonadism, characteristic pigmentation, or cirrhosis. Phlebotomy
    plays an important role in the management of endocrine complications
    of hemochromatosis, especially when diagnosis is early. In all cases
    of hypogonadotrophic hypogonadism, primary hemochromatosis must be
    considered.

    PMID: 17524608 [PubMed - as supplied by publisher]

    Who loves ya.
    Tom

    Jesus Was A Vegetarian!
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    DEAD PEOPLE WALKING
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  2. "disorders related to this disease are very rare and are described"

    A genetic disorder, not a meat eating disorder. The world is not black
    and white when it comes to iron.

    The hominids, of which we are menbers, have been eating meat for the
    past 3 million years or more.

  3. http://www.altsupportthyroid.org/pgdlines.php#disturbed

    <[email hidden]> wrote in message
    news:[email hidden]...

  4. Tumbleweed said:

    http://www.altsupportthyroid.org/pgdlines.php#disturbed

    <[email hidden]> wrote in message

    news:[email hidden]...

    Tumbleweed .. **finally** .. contributes ..

    Tumbleweed feels iron isn't involved in .. endocrine .. problems ..

    That would be based on his extensive .. intelligence .. IN ..
    medicine ..

    How's that .. feel ..

    To be one of the ONLY ones who .. believes .. iron doesn't cause
    endocrine .. problems ..

    It must be a .. struggle ..

    Do you think you will be able to convince everyone .. ?

    Maybe you should start .. gathering .. medical studies FOR .. your
    uphill battle .. ?

    Place .. ONE .. here .. (-)

    Just .. one ..

    And if you cannot .. place .. ONE ..?

    Means .. ?

    Not a .. good .. start ..

    Heh .. heh ..

    Who loves ya.
    Tom

    Jesus Was A Vegetarian!
    http://jesuswasavegetarian.7h.com

    Man Is A Herbivore!
    http://tinyurl.com/a3cc3

    DEAD PEOPLE WALKING
    http://tinyurl.com/zk9fk

  5. Quoted message said:
    Quoted message said:

    On May 27, 10:29 am, [email hidden] wrote: A genetic disorder, not a meat eating disorder. <<

    "Testing for iron
    overload is recommended in subjects with atypical type 2 diabetes
    (for
    example"

    Jeez .. they mentioned .. genetic .. BUT .. they didn't .. FIND ..
    genetic ..

    That .. means .. ?

    Genetics .. isn't .. **isn't** .. involved .. BUT .. iron overload ..
    IS .. that is why they .. **mention** .. testing FOR .. **iron
    overload** in those with type 2 diabetes ..

    You find some .. other .. reason .. WHY they say to test for iron
    overload .. IN .. type 2 diabetes .. ?

    Point .. it .. out ..

    Like the good contributor .. you .. are ..

    Who loves ya.
    Tom

    Jesus Was A Vegetarian!
    http://jesuswasavegetarian.7h.com

    Man Is A Herbivore!
    http://tinyurl.com/a3cc3

    DEAD PEOPLE WALKING
    http://tinyurl.com/zk9fk

  6. Quoted message said:
    Quoted message said:

    On May 27, 10:29 am, [email hidden] wrote A genetic disorder, not a meat eating disorder. <<

    Quoted message said:
    Quoted message said:

    On May 27, 10:29 am, [email hidden] wrote: A genetic disorder, not a meat eating disorder. <<

    "Testing for iron
    overload is recommended in subjects with atypical type 2 diabetes
    (for
    example"

    Jeez .. they mentioned .. genetic .. BUT .. they didn't .. FIND ..
    genetic ..

    That .. means .. ?

    Genetics .. isn't .. **isn't** .. involved .. BUT .. iron overload ..
    IS .. that is why they .. **mention** .. testing FOR .. **iron
    overload** in those with type 2 diabetes ..

    You find some .. other .. reason .. WHY they say to test for iron
    overload .. IN .. type 2 diabetes .. ?

    Point .. it .. out ..

    Like the good contributor .. you .. are ..

    Who loves ya.
    Tom

    Jesus Was A Vegetarian!
    http://jesuswasavegetarian.7h.com

    Man Is A Herbivore!
    http://tinyurl.com/a3cc3

    DEAD PEOPLE WALKING
    http://tinyurl.com/zk9fk

  7. "disorders related to this disease are very rare and are described"

    A genetic disorder, not a meat eating disorder. The world is not black
    and white when it comes to iron.

    The hominids, of which we are menbers, have been eating meat for the
    past 3 million years or more.

  8. Quoted message said:
    Quoted message said:

    On May 27, 10:29 am, [email hidden] wrote:


    "disorders related to this disease are very rare and are described"<<

    Time to .. step .. up .. boy ..

    "Other endocrine
    disorders related to this disease are very rare and are described
    especially in the most severe and earliest posttransfusion iron
    overloads. "

    Now you .. again .. specifically .. altered a medical study to make
    it .. appear .. as IF .. endocrine disorders are .. rare .. ON .. a
    thread about .. endocrine .. disorders ..

    Was that .. an .. accident .. ?

    Who loves ya.
    Tom

    Jesus Was A Vegetarian!
    http://jesuswasavegetarian.7h.com

    Man Is A Herbivore!
    http://tinyurl.com/a3cc3

    DEAD PEOPLE WALKING
    http://tinyurl.com/zk9fk

    Yes or .. no ..

    Quoted message said:


    A genetic disorder, not a meat eating disorder. The world is not black
    and white when it comes to iron.

    The hominids, of which we are menbers, have been eating meat for the
    past 3 million years or more.

  9. Quoted message said:
    Quoted message said:

    On May 27, 10:29 am, [email hidden] wrote:


    "disorders related to this disease are very rare and are described"<<

    Time to .. step .. up .. boy ..

    "Other endocrine
    disorders related to this disease are very rare and are described
    especially in the most severe and earliest posttransfusion iron
    overloads. "

    Now you .. again .. specifically .. altered a medical study to make
    it .. appear .. as IF .. endocrine disorders are .. rare .. ON .. a
    thread about .. endocrine .. disorders ..

    Was that .. an .. accident .. ?

    Yes or .. no ..

    Who loves ya.
    Tom

    Jesus Was A Vegetarian!
    http://jesuswasavegetarian.7h.com

    Man Is A Herbivore!
    http://tinyurl.com/a3cc3

    DEAD PEOPLE WALKING
    http://tinyurl.com/zk9fk

  10. http://www.altsupportthyroid.org/pgdlines.php#disturbed

    <[email hidden]> wrote in message
    news:[email hidden]...

  11. http://www.altsupportthyroid.org/pgdlines.php#disturbed

    <[email hidden]> wrote in message
    news:[email hidden]...

  12. http://www.altsupportthyroid.org/pgdlines.php#disturbed

    <[email hidden]> wrote in message
    news:[email hidden]...

  13. http://www.altsupportthyroid.org/pgdlines.php#disturbed

    <[email hidden]> wrote in message
    news:[email hidden]...

  14. http://www.altsupportthyroid.org/pgdlines.php#disturbed

    <[email hidden]> wrote in message
    news:[email hidden]...

  15. Hey .. tumbleweed .. here are some .. articles directed at ..
    children ..

    STEP .. on these .. posts .. too ..

    Like the big man .. you .. are ..

    Better watch that testosterone .. there .. tumble ..

    You're gonna need that when someone decides to bootfk .. ya ..

    Pissin yourself doesn't .. work .. really .. well ..

    Heh .. heh ..

    http://jcem.endojournals.org/cgi/content/abstract/76/2/357

    Journal of Clinical Endocrinology & Metabolism, Vol 76, 357-361,
    Copyright © 1993 by Endocrine Society

    --------------------------------------------------------------------------------

    ARTICLES

    Multiple hormone deficiencies in children with hemochromatosis
    KE Oerter, GA Kamp, PJ Munson, AW Nienhuis, FG Cassorla and PK
    Manasco
    Developmental Endocrinology Branch, National Institute of Child Health
    and Human Development, National Institutes of Health, Bethesda,
    Maryland 20892.

    Who loves ya.
    Tom

    Jesus Was A Vegetarian!
    http://jesuswasavegetarian.7h.com

    Man Is A Herbivore!
    http://tinyurl.com/a3cc3

    DEAD PEOPLE WALKING
    http://tinyurl.com/zk9fk

  16. How's that feel to have no testosterone .. tumble .. describe it ..

    So others can try to relate / understand insanity ..

    http://www.bmj.com/cgi/content/full/316/7135/915

    BMJ 1998;316:915-916 ( 21 March )

    Clinical review
    Lesson of the week

    Haemochromatosis as an endocrine cause of subfertility
    Haemochromatosis should be considered and iron studies performed when
    investigating endocrine causes of infertility
    Michael J Tweed, medical registrar, Jonathan M Roland, consultant
    physician.

    Who loves ya.
    Tom

    Jesus Was A Vegetarian!
    http://jesuswasavegetarian.7h.com

    Man Is A Herbivore!
    http://tinyurl.com/a3cc3

    DEAD PEOPLE WALKING
    http://tinyurl.com/zk9fk

  17. Look .. tumbleweed .. iron and endocrine disorders ..

    Should I show you how to find these types of articles .. ?

    Titre du document / Document title
    Primary hypothyroidism and multiple endocrine failure in association
    with hemochromatosis in a long-term hemodialysis patient
    Auteur(s) / Author(s)
    SHIROTA T. (1) ; SHINODA T. (1) ; AIZAWA T. (1) ; MIZUKAMI T. ;
    KATAKURA M. (1) ; TAKASU N. (1) ; YAMADA T. (1) ;
    Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)
    (1) Shinshu univ. school medicine, dep. geriatrics endocrinology
    metabolism, Asahi 3-chome, Matsumoto 390, JAPON

    Résumé / Abstract
    A 56-year-old male patient on chronic hemodialysis developed liver
    cirrhosis. He received a total of 20 liters of blood transfusion.
    Bronze pigmentation of the skin and iron deposition to the liver,
    spleen, pancreas and thyroid gland, which was demonstrated by computed
    tomography and magnetic resonance imaging studies, and histological
    demonstration of iron deposition to the thyroid gland, bone marrow and
    gastric mucosa established a diagnosis of secondary hemochromatosis.
    Endocrine work-up revealed the presence of diabetes mellitus with
    minimum insulin secretory response, primary (or thyroprivic)
    hypothyroidism, hypoparathyroidism and hypogonadotropic hypogonadism
    Revue / Journal Title
    Clinical nephrology (Clin. nephrol.) ISSN 0301-0430 CODEN CLNHBI
    Source / Source
    1992, vol. 38, no2, pp. 105-109 (15 ref.)
    Langue / Language
    Anglais

    Editeur / Publisher
    Dustri, München-Deisenhofen, ALLEMAGNE (1973) (Revue)

    Mots-clés anglais / English Keywords
    Renal failure ; Hemochromatosis ; Hypothyroidism ; Chronic ; Adult ;
    Male ; Complication ; Multiple organ failure ; Hemodialysis ;
    Treatment ; Extrarenal dialysis ; Case study ; Human ; Urinary system
    disease ; Renal disease ; Nephropathy ; Metabolic diseases ;
    Enzymopathy ; Pigments ; Iron ; Endocrinopathy ; Thyroid diseases ;
    Mots-clés français / French Keywords
    Insuffisance rénale ; Hémochromatose ; Hypothyroïdie ; Chronique ;
    Adulte ; Mâle ; Complication ; Insuffisance organique multiple ;
    Hémodialyse ; Traitement ; Epuration extrarénale ; Etude cas ; Homme ;
    Appareil urinaire pathologie ; Rein pathologie ; Néphropathie ;
    Métabolisme pathologie ; Enzymopathie ; Pigment ; Fer ;
    Endocrinopathie ; Thyroide pathologie ;

    002b14a05 ;
    Mots-clés espagnols / Spanish Keywords
    Insuficiencia renal ; Hemocromatosis ; Hipotiroidismo ; Crónico ;
    Adulto ; Macho ; Complicación ; Insuficiencia orgánica múltiple ;
    Hemodiálisis ; Tratamiento ; Depuración extrarrenal ; Estudio caso ;
    Hombre ; Aparato urinario patología ; Riñón patología ; Nefropatía ;
    Metabolismo patología ; Enzimopatía ; Pigmento ; Hierro ;
    Endocrinopatía ; Tiroides patología ;
    Localisation / Location
    INIST-CNRS, Cote INIST : 16768, 35400003603587.0090

    Copyright 2006 INIST-CNRS. All rights reserved

    Toute reproduction ou diffusion même partielle, par quelque procédé ou
    sur tout support que ce soit, ne pourra être faite sans l'accord
    préalable écrit de l'INIST-CNRS.
    No part of these records may be reproduced of distributed, in any form
    or by any means, without the prior written permission of INIST-CNRS.

    Nº notice refdoc (ud4) : 4720076

    Who loves ya.
    Tom

    Jesus Was A Vegetarian!
    http://jesuswasavegetarian.7h.com

    Man Is A Herbivore!
    http://tinyurl.com/a3cc3

    DEAD PEOPLE WALKING
    http://tinyurl.com/zk9fk

  18. Hey .. tumbleweed .. maybe iron is causing your .. lack OF
    testosterone .. ?

    http://clinicalstudies.info.nih.gov/detail/B_1985-H-0087.html

    Title: Clinical Course of Patients with Transfusional Hemochromatosis
    on Deferoxamine
    Number: 85-H-0087
    Summary: When patients receive repeated blood transfusions the level
    of iron in the patient's blood can rise. When iron is processed in the
    body a protein known as hemosiderin can begin collecting in the
    organs. If too much hemosiderin collects in the organs they can begin
    to malfunction. This condition is called transfusional
    hemochromatosis.

    Who loves ya.
    Tom

    Jesus Was A Vegetarian!
    http://jesuswasavegetarian.7h.com

    Man Is A Herbivore!
    http://tinyurl.com/a3cc3

    DEAD PEOPLE WALKING
    http://tinyurl.com/zk9fk

  19. http://www.emedicine.com/MED/topic975.htm

    Hemochromatosis

    Background: Hemochromatosis is the abnormal accumulation of iron in
    parenchymal organs, leading to organ toxicity. It is the most common
    inherited liver disease in whites and the most common autosomal
    recessive genetic disorder.

    Pathophysiology: Hereditary hemochromatosis is an adult-onset disorder
    characterized by inappropriately high iron absorption resulting in
    progressive iron overload. The organs involved are the liver, heart,
    pancreas, pituitary, joints, and skin.

    Adults preserve a constant level of body iron by efficient
    conservation, maintaining rigorous control over absorption to balance
    losses. An adult man loses approximately 1 mg of iron daily, mostly in
    desquamated epithelium and secretions from the gut and skin. During
    the childbearing years, healthy women lose an average of an additional
    milligram of iron daily from menstrual bleeding (40 mL blood loss) and
    approximately 500 mg with each pregnancy. In addition, normal daily
    fecal loss of approximately 0.7 mL of blood (0.3 mg of iron) occurs.
    Only a small quantity of iron is excreted in urine (<0.1 mg/d).

    Who loves ya.
    Tom

    Jesus Was A Vegetarian!
    http://jesuswasavegetarian.7h.com

    Man Is A Herbivore!
    http://tinyurl.com/a3cc3

    DEAD PEOPLE WALKING
    http://tinyurl.com/zk9fk

  20. How's that feel to have no testosterone .. tumble .. describe it ..

    So others can try to relate / understand insanity ..

    http://www.bmj.com/cgi/content/full/316/7135/915

    BMJ 1998;316:915-916 ( 21 March )

    Clinical review
    Lesson of the week

    Haemochromatosis as an endocrine cause of subfertility
    Haemochromatosis should be considered and iron studies performed when
    investigating endocrine causes of infertility
    Michael J Tweed, medical registrar, Jonathan M Roland, consultant
    physician.

    Who loves ya.
    Tom

    Jesus Was A Vegetarian!
    http://jesuswasavegetarian.7h.com

    Man Is A Herbivore!
    http://tinyurl.com/a3cc3

    DEAD PEOPLE WALKING
    http://tinyurl.com/zk9fk

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