Fibromyalgia an oxidative disorder

Yet another study on fibromyalgia that initially looks interesting to the casual reader. But look at
the significant statement, that the oxidation markers showed no correlation with either pain or
tender points. In other words, this is probably yet another case of the oxidative stress simply
either being a trigger for fibromyalgia, or being the result of fibromyalgia. Many health conditions
trigger fibromyalgia, and oxidative stress is one of many. In Turkey, it might happen to be a major
one, due to pollution and diet. Many people with fibromyalgia are deficient in magnesium, and a
magnesium deficiency can cause lipid peroxidation. Such studies do little to help people who already
have fibromyalgia, since taking antioxidants doesn't cure the pain in fibromyalgia. The damage is
done, at that point. So all such a study does is to give us another reason why oxidative stress is
bad you, as if we didn't know that to begin with?

In a previous article, [email hidden] (doe) wrote: ->Free radicals and antioxidants in
primary fibromyalgia: an oxidative stress ->disorder? ->Bagis S, Tamer L, Sahin G, Bilgin R, Guler
H, Ercan B, Erdogan C. ->Physical Medicine and Rehabilitation Department, Mersin University Medical
->School, Mersin, Turkey. ->The role of free radicals in fibromyalgia is controversial. In this
study, 85 ->female patients with primary fibromyalgia and 80 age-, height-, and ->weight-matched
healthy women were evaluated for oxidant/antioxidant balance. ->Malondialdehyde is a toxic
metabolite of lipid peroxidation used as a marker of ->free radical damage. Superoxide dismutase is
an intracellular antioxidant ->enzyme and shows antioxidant capacity. Pain was assessed by visual
analog ->scale. Tender points were assessed by palpation. Age, smoking, body mass index ->(BMI), and
duration of disease were also recorded. Malondialdehyde levels were ->significantly higher and
superoxide dismutase levels significantly lower in ->fibromyalgic patients than controls. Age, BMI,
smoking, and duration of disease ->did not affect these parameters. We found no correlation between
pain and ->number of tender points. In conclusion, oxidant/antioxidant balances were ->changed in
fibromyalgia. Increased free radical levels may be responsible for ->the development of
fibromyalgia. These findings may support the hypothesis of ->fibromyalgia as an oxidative disorder.
-> ->PMID: 14689230 [PubMed - as supplied by publisher] -> ->--------------------------------------------------------------------------
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