Anthony Cerrato <[email hidden]> wrote or quoted:
Quoted message said:"TJM" <[email hidden]> wrote:
Quoted message said:Quoted message said:I was wondering if there any good scientific books that
explains theories on how the primordial soup gave rise
to large organic macromolecules that were the precursors
to DNA and other cellular components. I prefer a text
that is geared toward the layperson, and not too heavy
on biochemistry.
You might take a look at "At Home in the Universe: The
Search for Laws of Self-Organization and Complexity" by
Stuart Kauffman (Paperback - October 1996)-- see reviews
at Amazon.com
Mostly a pop sci survey from the standpoint of chaos thy
(non-linear, dynamic systems thy) where the early chapters
describe his nonspecific overview of _possible_ prebiotic
evolution of life via autocatalytic enzymatic chain
reactions in dense chemical soups. The last half of the
book becomes a bit too overly specific as to fitness
landscapes, etc, for the casual reader (IMO.) I just
skinned those. He writes well though. [...]
While "At Home in the Universe" has virtues in some areas,
I find it exceptionally hard to stomach its "origin of
life" material.
The argument is of the form: imagine chemicals form
catalytic networks. We can simulate those networks using a
computer model...
It takes off from there - but never really comes back to
earth again to check to see if the whole idea is feasible.
For it to be so there needs to be a large collection of
viable autocatalaytic networks - connected by small
modifications - each preferentially catalysing its own
formation over that of its neighbours - without there being
template replicators involved to govern the process.
The reagents need to be rather inert for the scheme to work.
If all the components stick to each other, then the result
is a sticky mess - not a living organism.
The idea must be a difficult one to sell. All life we have
ever known is based around replication of physical
templates.
I would characterise Kauffman's OOL theory as not widely
accepted - and full of wild speculations.
I'm suprised at the popularily of the "autocatalytic
set" ideas.
They tend to share the problem of not having a terribly-
convincing information-transmission system - and that's the
very essence of life.
--
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