Quoted message said:Subject: Re: bladder infections From: [email hidden] (doe) Date: 9/20/2003 12:23 PM
Mountain Daylight Time Message-id: <[email hidden]>
Quoted message said:Subject: bladder infections From: [email hidden] (chelsy) Date: 9/20/2003 9:53 AM
Mountain Daylight Time Message-id: <[email hidden]>
I keep getting bladder infections just about every month, and I can't get rid of them! The docter
just gives me a bottle of pills, I take them, and they just keep coming back! They say if I drink
too much
Quoted message said:Quoted message said:I always do, so I think they're full of it! Does anyone know a different alterntive that I could
use instead of being on antibiotics that don't work for the rest of my life? Chelsy
Iron reduction therapy and vegetarian diet / low iron diet ....
For the rest of your life ..
Shock. 2003 Jul;20(1):52-5. Related Articles, Links
Iron overload before cecal ligation and puncture increases mortality.
Wizorek JJ, Turnbull IR, Buchman TG.
Department of Surgery, Washington University School of Medicine, 660 South Euclid Street, St. Louis,
MO 63110, USA.
Iron metabolism is dysregulated in critically ill patients. A mouse model of dysregulated iron
metabolism was used to examine the consequence of iron loading upon sepsis. Mice deleted in the hfe
gene (hfe-/-) abnormally accumulate iron in tissue; defects in the human hfe gene are clinically
expressed as hemochromatosis. Hfe-/- mice and wild-type counterparts were randomized to receive
either high- or low-iron diets for 2 weeks. After iron loading, mice were subjected to cecal
ligation and puncture (CLP), a clinically relevant animal model of intra-abdominal sepsis. A
preliminary (but underpowered) study suggested that iron-loaded hfe-/- mice had increased mortality
as compared with hfe-/- mice fed a low-iron diet. There was no difference between wild-type and
hfe-/- mice fed a low-iron diet or between wild-type mice fed hihg- and low-iron diets. A
subsequent, appropriately powered study showed that iron-loaded hfe-/- mice had significantly higher
mortality from intra-abdominal sepsis than hfe-/- mice fed a low-iron diet. Iron loading was
confirmed through chemical assay of iron concentration in hepatic tissue. Animals with dysregulated
iron handling, loaded with iron and subjected to CLP, had double the mortality of animals with
normal iron levels. Critical care patients often have altered iron metabolism. In clinical practice,
critically ill patients may receive iron through direct administration and the transfusion of blood
products. Iron therapy may adversely affect the clinical outcome from sepsis.
PMID: 12813369 [PubMed - indexed for MEDLINE]
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