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Cunego's naturally elevated hematocrit

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Road Cycling
Published
31 May 2004
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5 June 2004
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Shayana Kadidal
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  1. Velonews reports that Cunego has a naturally elevated hematocrit --
    presumably that means over 50% or close enough such that the 50% rule
    would create false positives if applied to him. In any event, they
    state he's allowed to race over 50%.

    So, a few questions:

    Anyone have any idea how they determine that someone has a naturally
    elevated hematocrit? (Historical test results back to your teens?
    Extended tests over the course of a year?)

    How high does your natural level have to be before they'll exempt you
    from the 50% rule? (47%? 49%? over 50?)

    Finally, I've read that high testosterone levels raise hematocrit --
    any idea if the naturally elevated h'crit population corresponds to
    the naturally elevated testosterone population?

    Surprisingly, I couldn't find answers in the archives. Would have
    thought these issues would have been thoroughly threshed out in
    1999.--Shayana Kadidal

  2. Shayana Kadidal said:

    Finally, I've read that high testosterone levels raise hematocrit --
    any idea if the naturally elevated h'crit population corresponds to
    the naturally elevated testosterone population?


    Do you have a reference for this?

  3. "Shayana Kadidal" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:

    Velonews reports that Cunego has a naturally elevated hematocrit --
    presumably that means over 50% or close enough such that the 50% rule
    would create false positives if applied to him. In any event, they
    state he's allowed to race over 50%.

    So, a few questions:

    Anyone have any idea how they determine that someone has a naturally
    elevated hematocrit? (Historical test results back to your teens?
    Extended tests over the course of a year?)

    How high does your natural level have to be before they'll exempt you
    from the 50% rule? (47%? 49%? over 50?)

    Finally, I've read that high testosterone levels raise hematocrit --
    any idea if the naturally elevated h'crit population corresponds to
    the naturally elevated testosterone population?

    Surprisingly, I couldn't find answers in the archives. Would have
    thought these issues would have been thoroughly threshed out in
    1999.--Shayana Kadidal

    Take a look here, this was a huge story in British cycling. Maybe theres
    some more info in the procycling archieves
    http://www.velonews.com/race/int/articles/5304.0.html

    Charley's father was also tested and found to have a naturally high level.
    This case was well documented in the British cycling press.

    Jan

  4. "Shayana Kadidal" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:

    Velonews reports that Cunego has a naturally elevated hematocrit --
    presumably that means over 50% or close enough such that the 50% rule
    would create false positives if applied to him. In any event, they
    state he's allowed to race over 50%.

    So, a few questions:

    Anyone have any idea how they determine that someone has a naturally
    elevated hematocrit? (Historical test results back to your teens?
    Extended tests over the course of a year?)

    If you keep failing or pushing the limit on haematocrit tests, but pass EPO
    tests, they'll probably take a look at your close family's haematocrit.

    It seems to be genetic; if one or both of your parents, who presumably have
    no reason to want an elevated haematocrit, nevertheless have one, then it
    strongly suggests that your haematocrit is where it is because of your
    parents not your 'supplements'.

    Since 'normal' is 40-ish percent, you'd expect to find some people whose
    genetics are such that they naturally sit close to 50%; you'd also expect to
    find some people who naturally sit near 30%. However sport in general will
    tend to select for the former and against the latter; not that haematocrit
    is the only thing that matters.

    Peter

  5. "Shayana Kadidal" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:


    Anyone have any idea how they determine that someone has a naturally
    elevated hematocrit? (Historical test results back to your teens?
    Extended tests over the course of a year?)

    Extended tests with no other indications of tampering are sufficient
    medically, but it also helps if your immediate family also shows elevated
    hematocrit. You can get a 'pass' for hamatocrits from 50-54% but I don't
    believe that you are allowed to race if you are above that.

    Quoted message said:

    Finally, I've read that high testosterone levels raise hematocrit --
    any idea if the naturally elevated h'crit population corresponds to
    the naturally elevated testosterone population?

    That's a new one on me. High testosterone doesn't relate closely to high
    hematocrit as far as I know.

  6. "Jan" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:

    "Shayana Kadidal" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:

    Velonews reports that Cunego has a naturally elevated hematocrit --
    presumably that means over 50% or close enough such that the 50% rule
    would create false positives if applied to him. In any event, they
    state he's allowed to race over 50%.

    So, a few questions:

    Anyone have any idea how they determine that someone has a naturally
    elevated hematocrit? (Historical test results back to your teens?
    Extended tests over the course of a year?)

    How high does your natural level have to be before they'll exempt you
    from the 50% rule? (47%? 49%? over 50?)

    Finally, I've read that high testosterone levels raise hematocrit --
    any idea if the naturally elevated h'crit population corresponds to
    the naturally elevated testosterone population?

    Surprisingly, I couldn't find answers in the archives. Would have
    thought these issues would have been thoroughly threshed out in
    1999.--Shayana Kadidal

    Take a look here, this was a huge story in British cycling. Maybe theres
    some more info in the procycling archieves
    http://www.velonews.com/race/int/articles/5304.0.html

    Charley's father was also tested and found to have a naturally high level.
    This case was well documented in the British cycling press

    ..
    Cunego and his father have both a natural level of 52-53 %. So he is indeed
    allowed to ride over 50 %. It doesn't seem fair. Isn't it possible to invent
    some product to rise the hematocrit level so his rivals could at least
    compete at equal terms?

    Benjo Maso

  7. benjo maso said:

    Cunego and his father have both a natural level of 52-53 %. So he is indeed
    allowed to ride over 50 %. It doesn't seem fair. Isn't it possible to invent
    some product to rise the hematocrit level so his rivals could at least
    compete at equal terms?

    Jacques Anquetil had a novel solution to expanding the gene pool to take
    care of this competition problem.

  8. "Shayana Kadidal" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:

    Velonews reports that Cunego has a naturally elevated hematocrit --
    presumably that means over 50% or close enough such that the 50% rule
    would create false positives if applied to him. In any event, they
    state he's allowed to race over 50%.

    So, a few questions:

    Anyone have any idea how they determine that someone has a naturally
    elevated hematocrit? (Historical test results back to your teens?
    Extended tests over the course of a year?)

    How high does your natural level have to be before they'll exempt you
    from the 50% rule? (47%? 49%? over 50?)

    Finally, I've read that high testosterone levels raise hematocrit --
    any idea if the naturally elevated h'crit population corresponds to
    the naturally elevated testosterone population?

    Surprisingly, I couldn't find answers in the archives. Would have
    thought these issues would have been thoroughly threshed out in
    1999.--Shayana Kadidal

    The answer as to the procedure is located on the UCI website although it
    takes some searching. In short, a person needs to have 4 blood tests
    (specific parameters) over the course of 6 weeks. The results must include
    a urine specific gravity. In addition, a hematologist must certify the
    results and write a letter stating that the person is otherwise healthy and
    that the high HCT is naturally occurring. The UCI then sets a level for
    that person that cannot be exceeded. For example, a person with a high
    hematocrit of 52 might have his level set at 53. One can then not exceed
    his specific limit.

    Here is the
    link..http://www.uci.ch/english/health_sante/docs_2003/UCI_certificate_2003.
    pdf

  9. "Kyle Legate" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:
    Shayana Kadidal said:

    Finally, I've read that high testosterone levels raise hematocrit --
    any idea if the naturally elevated h'crit population corresponds to
    the naturally elevated testosterone population?


    Do you have a reference for this?

    Testosterone is involved in the production of RBC so a link is possible.

  10. "Peter Allen" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:

    "Shayana Kadidal" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:

    Velonews reports that Cunego has a naturally elevated hematocrit --
    presumably that means over 50% or close enough such that the 50% rule
    would create false positives if applied to him. In any event, they
    state he's allowed to race over 50%.

    So, a few questions:

    Anyone have any idea how they determine that someone has a naturally
    elevated hematocrit? (Historical test results back to your teens?
    Extended tests over the course of a year?)

    If you keep failing or pushing the limit on haematocrit tests, but pass


    EPO

    Quoted message said:

    tests, they'll probably take a look at your close family's haematocrit.

    It seems to be genetic; if one or both of your parents, who presumably


    have

    Quoted message said:

    no reason to want an elevated haematocrit, nevertheless have one, then it
    strongly suggests that your haematocrit is where it is because of your
    parents not your 'supplements'.

    Since 'normal' is 40-ish percent, you'd expect to find some people whose
    genetics are such that they naturally sit close to 50%; you'd also expect


    to

    Quoted message said:

    find some people who naturally sit near 30%. However sport in general will
    tend to select for the former and against the latter; not that haematocrit
    is the only thing that matters.

    Peter

    Endurance training however tends to expand plasma volume far greater than
    the increase in RBC so hematocrit actually can be (and often is) lower in an
    endurance athlete. Seems backwards on the face of it.

  11. "Stewart Fleming" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:
    benjo maso said:

    Cunego and his father have both a natural level of 52-53 %. So he is


    indeed

    Quoted message said:
    Quoted message said:

    allowed to ride over 50 %. It doesn't seem fair. Isn't it possible to


    invent

    Quoted message said:
    Quoted message said:

    some product to rise the hematocrit level so his rivals could at least
    compete at equal terms?

    Jacques Anquetil had a novel solution to expanding the gene pool to take
    care of this competition problem.

    An interesting solution, but rather inefficient. Only one son! He should
    have thought of the gynaecologist in Milan Kundera's "The Farewell Party"
    who inseminated all of his patients with hin own sperm, hoping to have found
    a way that all men would become brothers...

    Benjo Maso

  12. benjo maso said:

    Cunego and his father have both a natural level of 52-53 %. So he is
    indeed allowed to ride over 50 %. It doesn't seem fair. Isn't it
    possible to invent some product to rise the hematocrit level so his
    rivals could at least compete at equal terms?

    I think there is a product on the market for this. It's called EPO or
    something like that. Yes it would definitely even out the score a bit.

    --
    Perre

    You have to be smarter than a robot to reply.

  13. "Sam" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:


    "Kyle Legate" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:
    Shayana Kadidal said:

    Finally, I've read that high testosterone levels raise hematocrit --
    any idea if the naturally elevated h'crit population corresponds to
    the naturally elevated testosterone population?


    Do you have a reference for this?

    Testosterone is involved in the production of RBC so a link is possible.


    A medline search using "testosterone rbc production" pulled up articles
    stating that testosterone affects erythroid glucose metabolism (no stated
    effect on proliferation or iron level), and a separate article suggests that
    test supplementation seems to have a slight effect on iron uptake in female
    rats only. An earlier search using "testosterone hematocrit" and
    "testosterone erythropoesis" gave nothing either. So now I'll have to ask
    you for references as well.

  14. The place I had read about the link between testosterone
    supplementation and high h'crit was on an impotence message board
    (which came up on a search, I wasn't browsing!), where they were
    discussing a poster's statement that he had tested at >50% h'crit
    after taking testosterone (presumably to treat the impotence). And
    another poster said that was not uncommon. (Not much of a "reference,"
    I know.)

    Don't men have higher h'crit than women, across the board?--Shayana
    Kadidal

    Quoted message said:

    That's a new one on me. High testosterone doesn't relate closely to high
    hematocrit as far as I know.

  15. "Shayana Kadidal" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:


    Don't men have higher h'crit than women, across the board?--Shayana

    According to Williams Hematology the normal range of men and women is:

    Men: 42-50% with a mean of 46% (mine is usually 48%)
    Women: 36-45% with a mean of 40%

    Women also have a higher percentage of body fat and muscle tissue that
    generates slightly less power. There is no way that women can generate the
    sort of power it takes to race with men of the same weight.

  16. Quoted message said:

    From: "Tom Kunich" [email hidden]

    Quoted message said:

    Men: 42-50% with a mean of 46% (mine is usually 48%)
    Women: 36-45% with a mean of 40%

    Women also have a higher percentage of body fat and muscle tissue that
    generates slightly less power. There is no way that women can generate the
    sort of power it takes to race with men of the same weight.

    Tom!
    How dare you cite science that contradicts the PC law that everyone is equal!
    Don't you know that Danny Devito, Arnold, Bev Francis, Sergio Oliva, and Lance
    all should have the same results no matter what the sport is? If not, someone
    has to file a discrimination, or hate crime lawsuit.
    Bill C

  17. TritonRider said:

    Tom!
    How dare you cite science that contradicts the PC law that everyone is
    equal! Don't you know that Danny Devito, Arnold, Bev Francis, Sergio
    Oliva, and Lance all should have the same results no matter what the
    sport is? If not, someone has to file a discrimination, or hate crime
    lawsuit. Bill C

    Taking lessons from the President, have you?
    http://www.washingtonpost.com/wp-dyn/articles/A4757-2004May31.html

  18. TritonRider said:

    Tom!
    How dare you cite science that contradicts the PC law that everyone is equal!

    You're tilting at straw men (sorry to mix only two metaphors; I couldn't
    think of a third).

  19. Kyle Legate said:

    A medline search using "testosterone rbc production" pulled up articles
    stating that testosterone affects erythroid glucose metabolism (no
    stated effect on proliferation or iron level), and a separate article
    suggests that test supplementation seems to have a slight effect on iron
    uptake in female rats only. An earlier search using "testosterone
    hematocrit" and "testosterone erythropoesis" gave nothing either. So now
    I'll have to ask you for references as well.

    Steroidal hormones can increase the total blood volume, which is
    independent of hematocrit (rbc concentration), although the overall
    effect may be similar (more rbcs = more O2).

    --

  20. Jan said:

    Take a look here, this was a huge story in British cycling. Maybe
    theres some more info in the procycling archieves http://www.velonews.-
    com/race/int/articles/5304.0.htmlhttp://www.velonews.com/race/int/arti-
    cles/5304.0.html

    In this case, the high hematocrit is almost certainly due to the
    rider's removed spleen. The spleen removes rbcs from the blood, so it
    seems logical.

    --

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