Diabetes mistery solved?

Where shall we send flowers?

It has one advantage, you WILL reduce your insulin
requirements, shortly to zero.

Why not just take willow bark - you will die slightly
sooner, than from that size doses of asprin, so will be in
extreme pain for a shorter period of time.

Stanimir said:

Hi all,

I found a rather old article in USA Today (Researchers
solve aspirin-diabetes mystery - usatoday.com2001 08 30Open ↗
aspirin.htm). Does anybody have more information about
this? In tree years by now, they should find replacement
for aspirin, that doesn't have aspirin's side effects. I'm
actually considering trying it for a short time, to see if
insulin resistance really goes away with such a high doses
of aspirin, but I have to find a way to take 14g of
aspirin per day with as little harm as possible. Any
thoughts, comments?

Stanimir

--
"...in addition to being foreign territory the past is, as
history, a hall of mirrors that reflect the needs of souls
observing from the present" Glen Cook

Here is more recent info on aspirin and diabetes control:

jci.org1321Open ↗

medscape.com474959Open ↗

The first used 7 g, about 20 regular size aspirin, per day.
The second used a med related to aspirin without the
digestive system side effects and 3 g per day. I would
consult my doc in either case, the first having the greater
potential for problems, the article saying don't do it
because of the problems, it was research only for a short
time only. The second is more promising, but caution still
remains. Lower amounts have benefits without the side
effects,ie. lower glycation and lower some cvd risk
factors; we are talking doses much smaller then those for
bg control above.

Quoted message said:

I found a rather old article in USA Today (Researchers
solve aspirin-diabetes mystery - usatoday.com2001 08 30Open ↗
aspirin.htm). Does anybody have more information about
this? In tree years by now, they should find replacement
for aspirin, that doesn't have aspirin's side effects. I'm
actually considering trying it for a short time, to see if
insulin resistance really goes away with such a high doses
of aspirin, but I have to find a way to take 14g of aspirin
per day with as little harm as possible. Any thoughts,
comments?

Stanimir

Thanks for your comments and opinions. Although I made a
mistake in my original post as right dosage is 7g or 14
tablets and not 14g, I see that you all agree with their
recommendations against trying such thing at home. I just
thought, they have clinical trials on volunteers, and maybe
there is a "safe" way doing it. However, I'm not running
into it and I will not do it at all if there is consensus
that it's outcome/risk ratio is low. I'll try to find more
info on net. Thanks again.

Regards, Stanimir

"Stanimir" <[email hidden]> wrote in message
"]news:[email hidden]...

Quoted message said:

Hi all,

I found a rather old article in USA Today (Researchers
solve aspirin-diabetes mystery - usatoday.com2001 08 30Open ↗
aspirin.htm). Does anybody have more information about
this? In tree years by now, they should find replacement
for aspirin, that doesn't have aspirin's side effects. I'm
actually considering trying it for a short time, to see if
insulin resistance really goes away with such a high doses
of aspirin, but I have

to

Quoted message said:

find a way to take 14g of aspirin per day with as little
harm as possible. Any thoughts, comments?

Stanimir

Quoted message said:

Stanimir said:

Hi all, I found a rather old article in USA Today
(Researchers solve aspirin-diabetes mystery - usatoday.com2001 08 30Open ↗
aspirin.htm). Does anybody have more information about
this? In tree years by now, they should find replacement
for aspirin, that doesn't have aspirin's side effects.
I'm actually considering trying it for a short time, to
see if insulin resistance really goes away with such a
high doses of aspirin, but I have to find a way to take
14g of aspirin per day with as little harm as possible.
Any thoughts, comments?

Ted Rosenberg said:

Where shall we send flowers? It has one advantage, you WILL
reduce your insulin requirements, shortly to zero. Why not
just take willow bark - you will die slightly sooner, than
from that size doses of asprin, so will be in extreme pain
for a shorter period of time.

I think you're going a bit overboard in your reaction.
Aspirin is generally given on a "2 tablets every 4 hours"
basis, so if you take one dose just after you get up and one
right before bed you will take 5 doses per day (10 tablets,
or 3.25 grams). This is in the "safe for just about
everybody" range. He is proposing a dosage that is a little
over four times as much. While there is an increased risk in
side effects, it seems quite far away from the doses that
would be lethal. I believe that when aspirin is used to
treat arthritis it is sometimes given in doses that high.

I would be aware of common side effects such as ringing in
the ears. Having blood counts periodically would be useful.
I would recommend taking enteric coated apirin to reduce the
chances of bleeding in the stomach. Ecotrim or a store-brand
or generic equivalent. However, I noted that the recent
study regarding blood CLOTTING indicated that enteric coated
aspirin was not nearly as effective as plain aspirin with
regard to that specific factor. I have no idea if there
would be any difference in the effect on insulin resistance,
but in light of that clotting report I would not say it's
impossible.

They said very emphatically that this wasn't recommended as
a home treatment, and I can't say that I blame them, but it
doesn't mean it is impossible for anyone to do. I will note,
however, that the caution is there for a reason. I once
needed to take aspirin for pain for a couple of months at
the "2 tablets every 4 hours" level. It caused sufficient
internal bleeding at that lower level that I was slightly
anemic - I was deferred as a blood donor for being about 10%
below their lower limit. At the higher doses he talks about
I would expect a stronger result =on me=, so this is not an
area I'm likely to experiment with.

Stanimir said:

Thanks for your comments and opinions. Although I made a
mistake in my original post as right dosage is 7g or 14
tablets and not 14g, I see that you all agree with their
recommendations against trying such thing at home. I just
thought, they have clinical trials on volunteers, and maybe
there is a "safe" way doing it. However, I'm not running
into it and I will not do it at all if there is consensus
that it's outcome/risk ratio is low. I'll try to find more
info on net. Thanks again. Regards, Stanimir

The standard aspirin tablet is 325 mg. 7g would be 21
standard tablets, not 14.

Quoted message said:

I think you're going a bit overboard in your reaction.
Aspirin is generally given on a "2 tablets every 4 hours"
basis, so if you take one dose just after you get up and
one right before bed you will take 5 doses per day (10
tablets, or 3.25 grams). This is in the "safe for just
about everybody" range. He is proposing a dosage that is a
little over four times as much. While there is an
increased risk in side effects, it seems quite far away
from the doses that would be lethal. I believe that when
aspirin is used to treat arthritis it is sometimes given
in doses that high.

I would be aware of common side effects such as ringing in
the ears. Having blood counts periodically would be useful.
I would recommend taking enteric coated apirin to reduce
the chances of bleeding in the stomach. Ecotrim or a store-
brand or generic equivalent. However, I noted that the
recent study regarding blood CLOTTING indicated that
enteric coated aspirin was not nearly as effective as plain
aspirin with regard to that specific factor. I have no idea
if there would be any difference in the effect on insulin
resistance, but in light of that clotting report I would
not say it's impossible.

They said very emphatically that this wasn't recommended as
a home treatment, and I can't say that I blame them, but it
doesn't mean it is impossible for anyone to do. I will
note, however, that the caution is there for a reason. I
once needed to take aspirin for pain for a couple of months
at the "2 tablets every 4 hours" level. It caused
sufficient internal bleeding at that lower level that I was
slightly anemic - I was deferred as a blood donor for being
about 10% below their lower limit. At the higher doses he
talks about I would expect a stronger result =on me=, so
this is not an area I'm likely to experiment with.

A real messed up stomach and excess bleeding are distinct
probable results. People have died from bleeding problems
attributed to excess aspirin use. When combined with some
other drugs it is a big problem.

I don't care what a person does, but over the years I have
had experiences that say go slow on the pill fixes. Make
sure they have a good benefit/risk ratio.

Like most of us, I have made mistakes. The only thing I have
seen working is good control and less eating.

Not the easy way but------------------------.