R
Roger
Guest
Radiat Med. 1998 May-Jun;16(3):195-200.
Response of unresectable pancreatic cancer to intraoperative radiotherapy.
Department of Radiology, Hirosaki University School of Medicine, Aomori, Japan.
Eight patients with unresectable pancreatic cancer were treated by intraoperative radiotherapy
(IORT) with electron beams, and the tumor responses were followed using serial CT scans. In five
cases, external beam irradiation with 10 MV X-rays was added. While there was no evident change
after 2-3 weeks, 6-8 weeks after IORT partial responses were noted in all five examined cases.
Furthermore, 12-16 weeks after IORT, three out of five examined patients showed good tumor response
with more than 75% regression. Mean survival time was 8.0 +/- 2.7 months. Two patients who lived
longer than 1.5 years had shown excellent tumor responses. Serial CT scans in the early period
following IORT allowed accurate estimation of the tumor response, which might predict some long-
surviving cases.
Response of unresectable pancreatic cancer to intraoperative radiotherapy.
Department of Radiology, Hirosaki University School of Medicine, Aomori, Japan.
Eight patients with unresectable pancreatic cancer were treated by intraoperative radiotherapy
(IORT) with electron beams, and the tumor responses were followed using serial CT scans. In five
cases, external beam irradiation with 10 MV X-rays was added. While there was no evident change
after 2-3 weeks, 6-8 weeks after IORT partial responses were noted in all five examined cases.
Furthermore, 12-16 weeks after IORT, three out of five examined patients showed good tumor response
with more than 75% regression. Mean survival time was 8.0 +/- 2.7 months. Two patients who lived
longer than 1.5 years had shown excellent tumor responses. Serial CT scans in the early period
following IORT allowed accurate estimation of the tumor response, which might predict some long-
surviving cases.