High Triglycerides

[email hidden] wrote in part:

Quoted message said:

My latest lipid profile (12 hour fast) included:

Total Cholesterol 185 HDL Cholesterol 40 Triglycerides 411

What concerns me most about these readings is the high triglyceride count. Is there a statin, or
some other medication, that would lower triglycerides to somewhere below 200?

Thanks,

Weight loss. Exercise. Reduced carbohydrate in the diet. Increased dietary fatty fish. Fish oil
supplementation.

It is usually easy to bring high TG down without drugs.
--
Jim Chinnis Warrenton, Virginia, USA

"Jim Chinnis" <[email hidden]> wrote in message
"]news:[email hidden]...
: [email hidden] wrote in part:
:
: >My latest lipid profile (12 hour fast) included:
: >
: >Total Cholesterol 185 HDL Cholesterol 40 Triglycerides 411
: >
: >What concerns me most about these readings is the high triglyceride count. Is there a statin, or
: >some other medication, that would lower triglycerides to somewhere below 200?
: >
: >Thanks,
:
: Weight loss. Exercise. Reduced carbohydrate in the diet. Increased dietary fatty fish. Fish oil
: supplementation.
:
: It is usually easy to bring high TG down without drugs.
: --

usually easy? could you cite a study(s) that would offer some support of this opinion?

Jim Chinnis said:

[email hidden] wrote in part:

Quoted message said:

My latest lipid profile (12 hour fast) included:

Total Cholesterol 185 HDL Cholesterol 40 Triglycerides 411

What concerns me most about these readings is the high triglyceride count. Is there a statin, or
some other medication, that would lower triglycerides to somewhere below 200?

Thanks,

Weight loss. Exercise. Reduced carbohydrate in the diet. Increased dietary fatty fish. Fish oil
supplementation.

It is usually easy to bring high TG down without drugs.

Would concur with the above and add:

(1) Permanent weight loss is not easily achievable by "commercial" dieting methods.

Would suggest that "noway" ask his/her doctor about the 2PD approach if s/he is overweight (BMI
more than 20):

heartmdphd.comwtloss.aspOpen ↗

(2) Exercise should be brisk walking or equivalent for at least 30 minutes daily right before the
evening meal.

(3) Reduced carbohydrate should not be interpreted as "low carb."

(4) Increased dietary fatty fish which implies higher overall intake should be interpreted as an
"exchange." I.e. instead a main course of steak/pork/chicken etc, try fatty fish. Since many
people don't like fish or are concerned about heavy metal poisoning, would suggest that "noway"
ask his/her doctor about omega-3 fatty acid supplements instead.

Humbly,

Andrew

--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
heartmdphd.comheartmdphd.comOpen ↗

"Dr. Andrew B. Chung, MD/PhD" <[email hidden]> wrote in message
"]news:[email hidden]...
: Jim Chinnis wrote:
:
: > [email hidden] wrote in part:
: >
: > >My latest lipid profile (12 hour fast) included:
: > >
: > >Total Cholesterol 185 HDL Cholesterol 40 Triglycerides 411
: > >
: > >What concerns me most about these readings is the high triglyceride count. Is there a statin,
: > >or some other medication, that would lower triglycerides to somewhere below 200?
: > >
: > >Thanks,
: >
: > Weight loss. Exercise. Reduced carbohydrate in the diet. Increased
dietary
: > fatty fish. Fish oil supplementation.
: >
: > It is usually easy to bring high TG down without drugs.
:
: Would concur with the above and add:
:
: (1) Permanent weight loss is not easily achievable by "commercial" dieting methods.
:
: Would suggest that "noway" ask his/her doctor about the 2PD approach if
s/he
: is overweight (BMI more than 20):
:
: heartmdphd.comwtloss.aspOpen ↗
:
: (2) Exercise should be brisk walking or equivalent for at least 30 minutes daily right before the
: evening meal.
:
: (3) Reduced carbohydrate should not be interpreted as "low carb."
:
: (4) Increased dietary fatty fish which implies higher overall intake
should be
: interpreted as an "exchange." I.e. instead a main course of steak/pork/chicken etc, try fatty
: fish. Since many people don't like fish
or
: are concerned about heavy metal poisoning, would suggest that "noway" ask his/her doctor about omega-
: 3 fatty acid supplements instead.
:

can you cite a study that will support the success of your opinion?

"Jim Horne" <[email hidden]> wrote in part:

Quoted message said:

"Jim Chinnis" <[email hidden]> wrote in message
"]news:[email hidden]...
: [email hidden] wrote in part:
:
: >My latest lipid profile (12 hour fast) included:
: >
: >Total Cholesterol 185 HDL Cholesterol 40 Triglycerides 411
: >
: >What concerns me most about these readings is the high triglyceride count. Is there a statin, or
: >some other medication, that would lower triglycerides to somewhere below 200?
: >
: >Thanks,
:
: Weight loss. Exercise. Reduced carbohydrate in the diet. Increased dietary fatty fish. Fish oil
: supplementation.
:
: It is usually easy to bring high TG down without drugs.
: --

usually easy? could you cite a study(s) that would offer some support of this opinion?

Not now. The holidays beckon.

I recall early studies (1980s?) reporting that BMI was the best predictor of serum triglycerides
and that level of exercise was the best predictor of HDL (which was low in the case of the
original poster).

More recent research has focused on the effects of long-chain omega-3 fatty acids, particulary DHA.

It was after reading a lot of the research that I tried this out myself. I'd say I dropped TG from
about 280 to 60 with weight loss, reduced carbs (refined starches), exercise (at least 50 minutes of
cardio 6 days a week at about 10 METs), and fish oil and DHA supplementation. HDL also doubled.

I agree that this is a sci.med group and cites are important. I just don't have the time to pull
together a good list right now, partly because I am advocating "combination therapy" which makes the
job a big one.
--
Jim Chinnis Warrenton, Virginia, USA

On Fri, 19 Dec 2003 13:57:35 -0500, Dr. Andrew B. Chung, MD/PhD wrote
(in message <[email hidden]>😉:

Quoted message said:

Jim Chinnis said:

[email hidden] wrote in part:

Quoted message said:

My latest lipid profile (12 hour fast) included:

Total Cholesterol 185 HDL Cholesterol 40 Triglycerides 411

What concerns me most about these readings is the high triglyceride count. Is there a statin, or
some other medication, that would lower triglycerides to somewhere below 200?

Thanks,

Weight loss. Exercise. Reduced carbohydrate in the diet. Increased dietary fatty fish. Fish oil
supplementation.

It is usually easy to bring high TG down without drugs.

Would concur with the above and add:

(1) Permanent weight loss is not easily achievable by "commercial" dieting methods.

Would suggest that "noway" ask his/her doctor about the 2PD approach if s/he is overweight (BMI
more than 20):

Would suggest that an easier protocol for "noway" to follow might be the 2FD approach. If has
several practical advantages over the 2PD approach and has a comparable scientific basis and
published success rate.

I developed the Two Foot Diet approach (2FD) as a replacement for Dr. Chung's Amazing Logic Defying
Two Pound Diet to avoid having to carry a scale around.

Inspired by Dr. Chung's scientific approach, as described on his website, in 2003, my wife and I
attended an IMAX film about climbing the Bavarian Alps and learned that despite their exhausting
regimen, the climbers consumed only 10 packages of wieners per week. That's less than 2 feet of
wieners per day! Since none of the climbers died from starvation, I think it is safe to assume that
2 feet of food per day should be more than adequate for us non-climbing folks.

So I started a little experiment with the agreeable obese friends in my neighborhood. I gave them
ordinary 6 inch rulers with instructions to measure the length of everything substantial that passed
into their mouths. The only things exempted were water and sugar-free drinks. What I learned was
that my obese friends were consuming between 8 to 12 feet of food per day! At the time, I was about
10 lbs. over my ideal body weight so I decided to find out how much I was eating per day... 3 feet.
I cut back to less than 2 feet and was at my proper weight in one month.

My friends have responded similarly except they have taken longer because of having to lose more
weight. Admittedly, some of my obese friends were especially slow to respond. They also happen to be
the ones with an unfortunate propensity for accidentally loosing their 6 inch rulers and taking
weeks to buy replacements.

So here's the deal: measure all the food you eat, using it's longest dimension, and keep the
total length to less than two feet per day. That's all there is. No scales, no counting calories
or carbohydrates. Heck, if you loose your ruler, you can even use the first joint of your thumb
to measure.

I am making this diet available as a public service and without compensation.

If you have any questions, just see Dr. Chung's helpful FAQ and substitute "Two Feet" for "Two
Pounds" everywhere... what could be simpler?

"If I have seen farther than others, it is because I have stood on the shoulders of midgets"

--

Steve

Fri, 19 Dec 2003 13:53:27 -0500 in article
<[email hidden]> "Jim Horne"

Quoted message said:

"Jim Chinnis" <[email hidden]> wrote in message
"]news:[email hidden]...
: [email hidden] wrote in part:
:
: >My latest lipid profile (12 hour fast) included:
: >
: >Total Cholesterol 185 HDL Cholesterol 40 Triglycerides 411
: >
: >What concerns me most about these readings is the high triglyceride count. Is there a statin, or
: >some other medication, that would lower triglycerides to somewhere below 200?
: >
: >Thanks,
:
: Weight loss. Exercise. Reduced carbohydrate in the diet. Increased dietary fatty fish. Fish oil
: supplementation.
:
: It is usually easy to bring high TG down without drugs.
: --

usually easy? could you cite a study(s) that would offer some support of this opinion?

Here some for the starters:

Parks EJ. Effect of dietary carbohydrate on triglyceride metabolism in humans. J Nutr. 2001 Oct;131(10):2772S-
2774S. Review. <http://www.nutrition.org/cgi/content/full/131/10/2772S>

Abbasi F, McLaughlin T, Lamendola C, Kim HS, Tanaka A, [censored] T, Nakajima K, Reaven GM. High
carbohydrate diets, triglyceride-rich lipoproteins, and coronary heart disease risk. Am J Cardiol.
2000 Jan 1;85(1):45-8. <ncbi.nlm.nih.govquery.fcgiOpen ↗
ids=11078235&dopt=Abstract>

McLaughlin T, Abbasi F, Lamendola C, Yeni-Komshian H, Reaven G. Carbohydrate-induced
hypertriglyceridemia: an insight into the link between plasma insulin and triglyceride
concentrations. J Clin Endocrinol Metab. 2000 Sep;85(9):3085-8.
<http://jcem.endojournals.org/cgi/content/full/85/9/3085>

Dallongeville J, Harbis A, Lebel P, Defoort C, Lairon D, Fruchart JC, Romon M. The plasma and
lipoprotein triglyceride postprandial response to a carbohydrate tolerance test differs in lean and
massively obese normolipidemic women. J Nutr. 2002 Aug;132(8):2161-6.
<http://www.nutrition.org/cgi/content/full/132/8/2161>

Hudgins LC. Effect of high-carbohydrate feeding on triglyceride and saturated fatty acid synthesis.
Proc Soc Exp Biol Med. 2000 Dec;225(3):178-83. <http://www.ebmonline.org/cgi/content/full/225/3/178>

Liu S, Manson JE, Stampfer MJ, Holmes MD, Hu FB, Hankinson SE, Willett WC. Dietary glycemic load
assessed by food-frequency questionnaire in relation to plasma high-density-lipoprotein cholesterol
and fasting plasma triacylglycerols in postmenopausal women. Am J Clin Nutr. 2001 Mar;73(3):560-6.
<http://www.ajcn.org/cgi/content/full/73/3/560>

West CE, Sullivan DR, Katan MB, Halferkamps IL, van der Torre HW. Boys from populations with high-
carbohydrate intake have higher fasting triglyceride levels than boys from populations with high-fat
intake. Am J Epidemiol. 1990 Feb;131(2):271-82. <ncbi.nlm.nih.govquery.fcgiOpen ↗
Retrieve&db=PubMed&list_uids=2296980&dopt=Abstract>

Silva ME, Pupo AA, Ursich MJ. Effects of a high-carbohydrate diet on blood glucose, insulin and
triglyceride levels in normal and obese subjects and in obese subjects with impaired glucose
tolerance. Braz J Med Biol Res. 1987;20(3-4):339-50. <ncbi.nlm.nih.govquery.fcgiOpen ↗
?cmd=Retrieve&db=PubMed&list_uids=3330460&dopt=Abstract>

Ullrich IH, Peters PJ, Albrink MJ. Effect of low-carbohydrate diets high in either fat or protein on
thyroid function, plasma insulin, glucose, and triglycerides in healthy young adults. J Am Coll
Nutr. 1985;4(4):451-9. <ncbi.nlm.nih.govquery.fcgiOpen ↗
ids=3900181&dopt=Abstract>

Koutsari C, Karpe F, Humphreys SM, Frayn KN, Hardman AE. Exercise prevents the accumulation of triglyceride-
rich lipoproteins and their remnants seen when changing to a high-carbohydrate diet. Arterioscler
Thromb Vasc Biol. 2001 Sep;21(9):1520-5. <http://atvb.ahajournals.org/cgi/content/full/21/9/1520>

Gyntelberg F, Brennan R, Holloszy JO, Schonfeld G, Rennie MJ, Weidman SW. Plasma triglyceride
lowering by exercise despite increased food intake in patients with type IV hyperlipoproteinemia. Am
J Clin Nutr. 1977 May;30(5):716-20. PMID: 193390 [PubMed - indexed for MEDLINE] <ncbi.nl-ncbi.nl-Open ↗
m.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=193390&dopt=Abstract>

Couillard C, Despres JP, Lamarche B, Bergeron J, Gagnon J, Leon AS, Rao DC, Skinner JS, Wilmore JH,
Bouchard C. Effects of endurance exercise training on plasma HDL cholesterol levels depend on levels
of triglycerides: evidence from men of the Health, Risk Factors, Exercise Training and Genetics
(HERITAGE) Family Study. Arterioscler Thromb Vasc Biol. 2001 Jul;21(7):1226-32. PMID: 11451756
[PubMed - indexed for MEDLINE] <http://atvb.ahajournals.org/cgi/content/full/21/7/1226>

Annuzzi G, Jansson E, Kaijser L, Holmquist L, Carlson LA. Increased removal rate of exogenous
triglycerides after prolonged exercise in man: time course and effect of exercise duration.
Metabolism. 1987 May;36(5):438-43. <ncbi.nlm.nih.govquery.fcgiOpen ↗
ubMed&list_uids=3574133&dopt=Abstract>

Sady SP, Thompson PD, Cullinane EM, Kantor MA, Domagala E, Herbert PN. Prolonged exercise augments
plasma triglyceride clearance. JAMA. 1986 Nov 14;256(18):2552-5. <ncbi.nlm.nih.goventreOpen ↗
z/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3773156&dopt=Abstract>

Moreno LA, Quintela I, Fleta J, Sarria A, Roda L, Giner A, Bueno M. Postprandial triglyceridemia in
obese and non-obese adolescents. Importance of body composition and fat distribution. J Pediatr
Endocrinol Metab. 2001 Feb;14(2):193-202. <ncbi.nlm.nih.govquery.fcgiOpen ↗
ve&db=PubMed&list_uids=11305798&dopt=Abstract>

Mekki N, Christofilis MA, Charbonnier M, Atlan-Gepner C, Defoort C, Juhel C, Borel P, Portugal H,
Pauli AM, Vialettes B, Lairon D. Influence of obesity and body fat distribution on postprandial
lipemia and triglyceride-rich lipoproteins in adult women. J Clin Endocrinol Metab. 1999 Jan;84(1):184-
91. <http://jcem.endojournals.org/cgi/content/full/84/1/184>

Dhurandhar NV, Kulkarni PR. Serum cholesterol and triglyceride levels in weight reduction program
dropouts. Int J Food Sci Nutr. 1995 Feb;46(1):17-20. <ncbi.nlm.nih.govquery.fcgiOpen ↗
?cmd=Retrieve&db=PubMed&list_uids=7712338&dopt=Abstract>

Sonnichsen AC, Ritter MM, Mohrle W, Richter WO, Schwandt P. The waist-to-hip ratio corrected for
body mass index is related to serum triglycerides and high-density lipoprotein cholesterol but not
to parameters of glucose metabolism in healthy premenopausal women. <ncbi.nlm.nih.govenOpen ↗
trez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8312684&dopt=Abstract>

Whitmore L, Trejos A, Mata L. Serum cholesterol, triglyceride, and high-density-lipoprotein
concentrations in men with different dietary and exercise regimens in Puriscal, Costa Rica. Arch
Latinoam Nutr. 1986 Jun;36(2):237-46. <ncbi.nlm.nih.govquery.fcgiOpen ↗
b=PubMed&list_uids=3632203&dopt=Abstract>

Chan DC, Watts GF, Mori TA, Barrett PH, Redgrave TG, Beilin LJ. Randomized controlled trial of the
effect of n-3 fatty acid supplementation on the metabolism of apolipoprotein B-100 and chylomicron
remnants in men with visceral obesity. Am J Clin Nutr. 2003 Feb;77(2):300-7. PMID: 12540386 [PubMed
- indexed for MEDLINE] <ncbi.nlm.nih.govquery.fcgiOpen ↗
ids=12540386&dopt=Abstract>

Jonkers IJ, Smelt AH, Ledeboer M, Hollum ME, Biemond I, Kuipers F, Stellaard F, Boverhof R, Meinders
AE, Lamers CH, Masclee AA. Gall bladder dysmotility: a risk factor for gall stone formation in
hypertriglyceridaemia and reversal on triglyceride lowering therapy by bezafibrate and fish oil.
Gut. 2003 Jan;52(1):109-15. PMID: 12477770 [PubMed - indexed for MEDLINE] <ncbi.nlm.nih.-ncbi.nlm.nih.-Open ↗
gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12477770&dopt=Abstract>

Durrington PN, Bhatnagar D, Mackness MI, Morgan J, Julier K, Khan MA, France M. An omega-3
polyunsaturated fatty acid concentrate administered for one year decreased triglycerides in
simvastatin treated patients with coronary heart disease and persisting hypertriglyceridaemia.
Heart. 2001 May;85(5):544-8. PMID: 11303007 [PubMed - indexed for MEDLINE] <ncbi.nlm.nih-ncbi.nlm.nih-Open ↗
.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11303007&dopt=Abstract>

Stark KD, Park EJ, Maines VA, Holub BJ. Effect of a fish-oil concentrate on serum lipids in
postmenopausal women receiving and not receiving hormone replacement therapy in a placebo-
controlled, double-blind trial. Am J Clin Nutr. 2000 Aug;72(2):389-94. PMID: 10919932 [PubMed -
indexed for MEDLINE] <http://www.ajcn.org/cgi/content/full/72/2/389>

Weber P, Raederstorff D. Triglyceride-lowering effect of omega-3 LC-polyunsaturated fatty acids--a
review. Nutr Metab Cardiovasc Dis. 2000 Feb;10(1):28-37. Review. PMID: 10812585 <ncbi.nl-ncbi.nl-Open ↗
m.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10812585&dopt=Abstract>

Harris WS. Nonpharmacologic treatment of hypertriglyceridemia: focus on fish oils. Clin Cardiol.
1999 Jun;22(6 Suppl):II40-3. Review. PMID: 10376196 [PubMed - indexed for MEDLINE] <ncbi-ncbi-Open ↗
.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10376196&dopt=Abstract>

Marckmann P, Bladbjerg EM, Jespersen J. Dietary fish oil (4 g daily) and cardiovascular risk markers
in healthy men. Arterioscler Thromb Vasc Biol. 1997 Dec;17(12):3384-91. PMID: 9437183 [PubMed -
indexed for MEDLINE] <ncbi.nlm.nih.govquery.fcgiOpen ↗
s=9437183&dopt=Abstract>

Roche HM, Gibney MJ. Postprandial triacylglycerolaemia: the effect of low-fat dietary treatment with
and without fish oil supplementation. Eur J Clin Nutr. 1996 Sep;50(9):617-24. PMID: 8880041 [PubMed
- indexed for MEDLINE] <ncbi.nlm.nih.govquery.fcgiOpen ↗
ids=8880041&dopt=Abstract>

Mori TA, Vandongen R, Beilin LJ, Burke V, Morris J, Ritchie J. Effects of varying dietary fat, fish,
and fish oils on blood lipids in a randomized controlled trial in men at risk of heart disease. Am J
Clin Nutr. 1994 May;59(5):1060-8. PMID: 8172092 [PubMed - indexed for MEDLINE] <ncbi.nlm-ncbi.nlm-Open ↗
.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8172092&dopt=Abstract>

Tato F, Keller C, Wolfram G. Effects of fish oil concentrate on lipoproteins and apolipoproteins in
familial combined hyperlipidemia. Clin Investig. 1993 Apr;71(4):314-8. PMID: 8471818 [PubMed -
indexed for MEDLINE] <ncbi.nlm.nih.govquery.fcgiOpen ↗
s=8471818&dopt=Abstract>

Zakaria B, Bertsch S. [Low-dose omega-3 fatty acids as lipid lowering agents in the practice. A
field study of ambulatory patients in general practice] Fortschr Med. 1992 Apr 10;110(10):178-82.
German. PMID: 1577358 [PubMed - indexed for MEDLINE] <ncbi.nlm.nih.govquery.fcgiOpen ↗
?cmd=Retrieve&db=PubMed&list_uids=1577358&dopt=Abstract>

Bairati I, Roy L, Meyer F. Effects of a fish oil supplement on blood pressure and serum lipids in
patients treated for coronary artery disease. Can J Cardiol. 1992 Jan-Feb;8(1):41-6. PMID: 1617510
[PubMed - indexed for MEDLINE] <ncbi.nlm.nih.govquery.fcgiOpen ↗
d&list_uids=1617510&dopt=Abstract>

Burr ML. Fish food, fish oil and cardiovascular disease. Clin Exp Hypertens A. 1992;14(1-2):181-92.
Review. PMID: 1541036 [PubMed - indexed for MEDLINE] <ncbi.nlm.nih.govquery.fcgiOpen ↗
?cmd=Retrieve&db=PubMed&list_uids=1541036&dopt=Abstract>

Deslypere JP. Influence of supplementation with N-3 fatty acids on different coronary risk factors
in men--a placebo controlled study. Verh K Acad Geneeskd Belg. 1992;54(3):189-216. PMID: 1413984
[PubMed - indexed for MEDLINE] <ncbi.nlm.nih.govquery.fcgiOpen ↗
d&list_uids=1413984&dopt=Abstract>

Harris WS, Windsor SL, Dujovne CA. Effects of four doses of n-3 fatty acids given to hyperlipidemic
patients for six months. J Am Coll Nutr. 1991 Jun;10(3):220-7. PMID: 1832701 [PubMed - indexed for
MEDLINE] <ncbi.nlm.nih.govquery.fcgiOpen ↗
pt=Abstract>

Terres W, Beil U, Reimann B, Tiede S, Bleifeld W. [Low-dose fish oil in primary
hypertriglyceridemia. A randomized placebo-controlled study] Z Kardiol. 1991 Jan;80(1):20-4. German.
PMID: 2035283 [PubMed - indexed for MEDLINE] <ncbi.nlm.nih.govquery.fcgiOpen ↗
rieve&db=PubMed&list_uids=2035283&dopt=Abstract>

DeLany JP, Vivian VM, Snook JT, Anderson PA. Effects of fish oil on serum lipids in men during a
controlled feeding trial. Am J Clin Nutr. 1990 Sep;52(3):477-85. PMID: 2203252 [PubMed - indexed for
MEDLINE] <ncbi.nlm.nih.govquery.fcgiOpen ↗
pt=Abstract>

Bohn KA, Friisk CF, Boe OW, Hysing J. [Effect on the lipid profile of diet supplemented with fish
oil concentrate] Tidsskr Nor Laegeforen. 1990 May 20;110(13):1693-6. Norwegian. PMID: 2195704
[PubMed - indexed for MEDLINE] <ncbi.nlm.nih.govquery.fcgiOpen ↗
d&list_uids=2195704&dopt=Abstract>

Radack KL, Deck CC, Huster GA. n-3 fatty acid effects on lipids, lipoproteins, and apolipoproteins
at very low doses: results of a randomized controlled trial in hypertriglyceridemic subjects. Am J
Clin Nutr. 1990 Apr;51(4):599-605. PMID: 2181859 [PubMed - indexed for MEDLINE] <ncbi.nl-ncbi.nl-Open ↗
m.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2181859&dopt=Abstract>

Bhathena SJ, Ali AA, Haudenschild C, Latham P, Ranich T, Mohamed AI, Hansen CT, Velasquez MT.
Dietary Flaxseed Meal is More Protective Than Soy Protein Concentrate Against Hypertriglyceridemia
and Steatosis of the Liver in an Animal Model of Obesity. J Am Coll Nutr. 2003 Apr;22(2):157-64.
PMID: 12672712 [PubMed - in process] <ncbi.nlm.nih.govquery.fcgiOpen ↗
=PubMed&list_uids=12672712&dopt=Abstract>

--
Matti Narkia

"Jim Chinnis" <[email hidden]> wrote in message
"]news:[email hidden]...
: "Jim Horne" <[email hidden]> wrote in part:
:
: >
: >"Jim Chinnis" <[email hidden]> wrote in message
: >"]news:[email hidden]...
: >: [email hidden] wrote in part:
: >:
: >: >My latest lipid profile (12 hour fast) included:
: >: >
: >: >Total Cholesterol 185 HDL Cholesterol 40 Triglycerides 411
: >: >
: >: >What concerns me most about these readings is the high triglyceride count. Is there a statin,
: >: >or some other medication, that would lower triglycerides to somewhere below 200?
: >: >
: >: >Thanks,
: >:
: >: Weight loss. Exercise. Reduced carbohydrate in the diet. Increased
dietary
: >: fatty fish. Fish oil supplementation.
: >:
: >: It is usually easy to bring high TG down without drugs.
: >: --
: >
: >usually easy? could you cite a study(s) that would offer some support of this opinion?
:
: Not now. The holidays beckon.
:
: I recall early studies (1980s?) reporting that BMI was the best predictor
of
: serum triglycerides and that level of exercise was the best predictor of
HDL
: (which was low in the case of the original poster).
:
: More recent research has focused on the effects of long-chain omega-3
fatty
: acids, particulary DHA.
:
: It was after reading a lot of the research that I tried this out myself.
I'd
: say I dropped TG from about 280 to 60 with weight loss, reduced carbs
(refined
: starches), exercise (at least 50 minutes of cardio 6 days a week at about
10
: METs), and fish oil and DHA supplementation. HDL also doubled.
:
: I agree that this is a sci.med group and cites are important. I just don't have the time to pull
: together a good list right now, partly because I am advocating "combination therapy" which makes
: the job a big one.
: --
Thanks, Jim. The biggest issue is I suffer from metabolic syndrome and diet and exercise alone
has had very little positive effect in controlling the triglycerides. LDL reduction was improved
some and the HDL favored well. TGs were around 100 at my last visit, however I'm on lipid
medication to control.

Jim Chinnis said:

"Jim Horne" <[email hidden]> wrote in part:

Quoted message said:

"Jim Chinnis" <[email hidden]> wrote in message
"]news:[email hidden]...
: [email hidden] wrote in part:
:
: >My latest lipid profile (12 hour fast) included:
: >
: >Total Cholesterol 185 HDL Cholesterol 40 Triglycerides 411
: >
: >What concerns me most about these readings is the high triglyceride count. Is there a statin,
: >or some other medication, that would lower triglycerides to somewhere below 200?
: >
: >Thanks,
:
: Weight loss. Exercise. Reduced carbohydrate in the diet. Increased dietary fatty fish. Fish oil
: supplementation.
:
: It is usually easy to bring high TG down without drugs.
: --

usually easy? could you cite a study(s) that would offer some support of this opinion?

Not now. The holidays beckon.

I recall early studies (1980s?) reporting that BMI was the best predictor of serum triglycerides
and that level of exercise was the best predictor of HDL (which was low in the case of the
original poster).

More recent research has focused on the effects of long-chain omega-3 fatty acids,
particulary DHA.

It was after reading a lot of the research that I tried this out myself. I'd say I dropped TG from
about 280 to 60 with weight loss, reduced carbs (refined starches), exercise (at least 50 minutes
of cardio 6 days a week at about 10 METs), and fish oil and DHA supplementation. HDL also doubled.

I agree that this is a sci.med group and cites are important. I just don't have the time to pull
together a good list right now, partly because I am advocating "combination therapy" which makes
the job a big one.
--
Jim Chinnis Warrenton, Virginia, USA

That's ok, Jim. I'll vouch for you that it is relatively "easy" (the term "relative" is used here
because for some folks being civil, which should be easy, is difficult). Others (ie Matti, who would
be an example of someone with the aforementioned difficulty) have posted more than enough references
here on SMC to convince folks that Omega-3 fatty acids are cardiovascularly beneficial. There have
also been enough cites to support exercise and weight loss as favorable for improving lipid profile.
Mr. Horne (another example) knows how to Google.

May you have a blessed Christmas, Jim.

Humbly,

Andrew

--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
heartmdphd.comheartmdphd.comOpen ↗

"Dr. Andrew B. Chung, MD/PhD" <[email hidden]> wrote in message
"]news:[email hidden]...
: Jim Chinnis wrote:
:
: > "Jim Horne" <[email hidden]> wrote in part:
: >
: > >
: > >"Jim Chinnis" <[email hidden]> wrote in message
: > >"]news:[email hidden]...
: > >: [email hidden] wrote in part:
: > >:
: > >: >My latest lipid profile (12 hour fast) included:
: > >: >
: > >: >Total Cholesterol 185 HDL Cholesterol 40 Triglycerides 411
: > >: >
: > >: >What concerns me most about these readings is the high triglyceride count. Is there a
: > >: >statin, or some other medication, that would lower triglycerides to somewhere below 200?
: > >: >
: > >: >Thanks,
: > >:
: > >: Weight loss. Exercise. Reduced carbohydrate in the diet. Increased
dietary
: > >: fatty fish. Fish oil supplementation.
: > >:
: > >: It is usually easy to bring high TG down without drugs.
: > >: --
: > >
: > >usually easy? could you cite a study(s) that would offer some support
of
: > >this opinion?
: >
: > Not now. The holidays beckon.
: >
: > I recall early studies (1980s?) reporting that BMI was the best
predictor of
: > serum triglycerides and that level of exercise was the best predictor of
HDL
: > (which was low in the case of the original poster).
: >
: > More recent research has focused on the effects of long-chain omega-3
fatty
: > acids, particulary DHA.
: >
: > It was after reading a lot of the research that I tried this out myself.
I'd
: > say I dropped TG from about 280 to 60 with weight loss, reduced carbs
(refined
: > starches), exercise (at least 50 minutes of cardio 6 days a week at
about 10
: > METs), and fish oil and DHA supplementation. HDL also doubled.
: >
: > I agree that this is a sci.med group and cites are important. I just
don't
: > have the time to pull together a good list right now, partly because I
am
: > advocating "combination therapy" which makes the job a big one.
: > --
: > Jim Chinnis Warrenton, Virginia, USA
:
: That's ok, Jim. I'll vouch for you that it is relatively "easy"

but he said "usually easy" very different from "relatively "easy""

and no need for me to Google, I have a full arsenal of fine physicians at my disposal, some you just
may have worked with or for in the past few years...

I also had problems with my cholesterol & Triglycerides
My Doctor has me on 80 mg lipitor also recently added a drug called zitia
for my cholesterol.The numbers are good. For my Triglycerides he has me on a
drug called Lopid, I take 600 mg twice a day. This seems to do a good job.
Check with your Cardiologist or Primary about this drug
.
<[email hidden]> wrote in message "]news:[email hidden]...

Quoted message said:

My latest lipid profile (12 hour fast) included:

Total Cholesterol 185 HDL Cholesterol 40 Triglycerides 411

What concerns me most about these readings is the high triglyceride count. Is there a statin, or
some other medication, that would lower triglycerides to somewhere below 200?

Thanks,

"Jim Horne" <[email hidden]> wrote in message news:<[email hidden]>...

Quoted message said:

"Dr. Andrew B. Chung, MD/PhD" <[email hidden]> wrote in message
"]news:[email hidden]...
: Jim Chinnis wrote:
:
: > "Jim Horne" <[email hidden]> wrote in part:
: >
: > >
: > >"Jim Chinnis" <[email hidden]> wrote in message
: > >"]news:[email hidden]...
: > >: [email hidden] wrote in part:
: > >:
: > >: >My latest lipid profile (12 hour fast) included:
: > >: >
: > >: >Total Cholesterol 185 HDL Cholesterol 40 Triglycerides 411
: > >: >
: > >: >What concerns me most about these readings is the high triglyceride count. Is there a
: > >: >statin, or some other medication, that would lower triglycerides to somewhere below 200?
: > >: >
: > >: >Thanks,
: > >:
: > >: Weight loss. Exercise. Reduced carbohydrate in the diet. Increased
dietary
: > >: fatty fish. Fish oil supplementation.
: > >:
: > >: It is usually easy to bring high TG down without drugs.
: > >: --
: > >
: > >usually easy? could you cite a study(s) that would offer some support
of
: > >this opinion?
: >
: > Not now. The holidays beckon.
: >
: > I recall early studies (1980s?) reporting that BMI was the best
predictor of
: > serum triglycerides and that level of exercise was the best predictor of
HDL
: > (which was low in the case of the original poster).
: >
: > More recent research has focused on the effects of long-chain omega-3
fatty
: > acids, particulary DHA.
: >
: > It was after reading a lot of the research that I tried this out myself.
I'd
: > say I dropped TG from about 280 to 60 with weight loss, reduced carbs
(refined
: > starches), exercise (at least 50 minutes of cardio 6 days a week at
about 10
: > METs), and fish oil and DHA supplementation. HDL also doubled.
: >
: > I agree that this is a sci.med group and cites are important. I just
don't
: > have the time to pull together a good list right now, partly because I
am
: > advocating "combination therapy" which makes the job a big one.
: > --
: > Jim Chinnis Warrenton, Virginia, USA
:
: That's ok, Jim. I'll vouch for you that it is relatively "easy"

but he said "usually easy" very different from "relatively "easy""

and no need for me to Google, I have a full arsenal of fine physicians at my disposal, some you
just may have worked with or for in the past few years...

Neither would necessarily make them "fine"

Humbly,

Andrew

--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
heartmdphd.comheartmdphd.comOpen ↗

I have access top pubmed and all the other data baes, despite this all I can get is the abstract to
all of these articles. How do I get a PDF of the article from pubmed or medline?

Thank You, Robert Kershaw

Matti Narkia said:

Fri, 19 Dec 2003 13:53:27 -0500 in article <[email hidden]> "Jim

Horne said:

"Jim Chinnis" <[email hidden]> wrote in message
"]news:[email hidden]...
: [email hidden] wrote in part:
:
: >My latest lipid profile (12 hour fast) included:
: >
: >Total Cholesterol 185 HDL Cholesterol 40 Triglycerides 411
: >
: >What concerns me most about these readings is the high triglyceride count. Is there a statin,
: >or some other medication, that would lower triglycerides to somewhere below 200?
: >
: >Thanks,
:
: Weight loss. Exercise. Reduced carbohydrate in the diet. Increased dietary fatty fish. Fish oil
: supplementation.
:
: It is usually easy to bring high TG down without drugs.
: --

usually easy? could you cite a study(s) that would offer some support of this opinion?

Here some for the starters:

Parks EJ. Effect of dietary carbohydrate on triglyceride metabolism in humans. J Nutr. 2001 Oct;131(10):2772S-
2774S. Review. <http://www.nutrition.org/cgi/content/full/131/10/2772S>

Abbasi F, McLaughlin T, Lamendola C, Kim HS, Tanaka A, [censored] T, Nakajima K, Reaven GM. High
carbohydrate diets, triglyceride-rich lipoproteins, and coronary heart disease risk. Am J Cardiol.
2000 Jan 1;85(1):45-8. <ncbi.nlm.nih.govquery.fcgiOpen ↗
uids=11078235&dopt=Abstract>

McLaughlin T, Abbasi F, Lamendola C, Yeni-Komshian H, Reaven G. Carbohydrate-induced
hypertriglyceridemia: an insight into the link between plasma insulin and triglyceride
concentrations. J Clin Endocrinol Metab. 2000 Sep;85(9):3085-8.
<http://jcem.endojournals.org/cgi/content/full/85/9/3085>

Dallongeville J, Harbis A, Lebel P, Defoort C, Lairon D, Fruchart JC, Romon M. The plasma and
lipoprotein triglyceride postprandial response to a carbohydrate tolerance test differs in lean and
massively obese normolipidemic women. J Nutr. 2002 Aug;132(8):2161-6.
<http://www.nutrition.org/cgi/content/full/132/8/2161>

Hudgins LC. Effect of high-carbohydrate feeding on triglyceride and saturated fatty acid synthesis.
Proc Soc Exp Biol Med. 2000 Dec;225(3):178-83.
<http://www.ebmonline.org/cgi/content/full/225/3/178>

Liu S, Manson JE, Stampfer MJ, Holmes MD, Hu FB, Hankinson SE, Willett WC. Dietary glycemic load
assessed by food-frequency questionnaire in relation to plasma high-density-lipoprotein cholesterol
and fasting plasma triacylglycerols in postmenopausal women. Am J Clin Nutr. 2001 Mar;73(3):560-6.
<http://www.ajcn.org/cgi/content/full/73/3/560>

West CE, Sullivan DR, Katan MB, Halferkamps IL, van der Torre HW. Boys from populations with high-
carbohydrate intake have higher fasting triglyceride levels than boys from populations with high-
fat intake. Am J Epidemiol. 1990 Feb;131(2):271-82. <ncbi.nlm.nih.govquery.fcgiOpen ↗
?cmd=Retrieve&db=PubMed&list_uids=2296980&dopt=Abstract>

Silva ME, Pupo AA, Ursich MJ. Effects of a high-carbohydrate diet on blood glucose, insulin and
triglyceride levels in normal and obese subjects and in obese subjects with impaired glucose
tolerance. Braz J Med Biol Res. 1987;20(3-4):339-50. <ncbi.nlm.nih.govquery.fcgOpen ↗
i?cmd=Retrieve&db=PubMed&list_uids=3330460&dopt=Abstract>

Ullrich IH, Peters PJ, Albrink MJ. Effect of low-carbohydrate diets high in either fat or protein
on thyroid function, plasma insulin, glucose, and triglycerides in healthy young adults. J Am Coll
Nutr. 1985;4(4):451-9. <ncbi.nlm.nih.govquery.fcgiOpen ↗
uids=3900181&dopt=Abstract>

Koutsari C, Karpe F, Humphreys SM, Frayn KN, Hardman AE. Exercise prevents the accumulation of triglyceride-
rich lipoproteins and their remnants seen when changing to a high-carbohydrate diet. Arterioscler
Thromb Vasc Biol. 2001 Sep;21(9):1520-5. <http://atvb.ahajournals.org/cgi/content/full/21/9/1520>

Gyntelberg F, Brennan R, Holloszy JO, Schonfeld G, Rennie MJ, Weidman SW. Plasma triglyceride
lowering by exercise despite increased food intake in patients with type IV hyperlipoproteinemia.
Am J Clin Nutr. 1977 May;30(5):716-20. PMID: 193390 [PubMed - indexed for MEDLINE] <ncb-ncb-Open ↗
i.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=193390&dopt=Abstract>

Couillard C, Despres JP, Lamarche B, Bergeron J, Gagnon J, Leon AS, Rao DC, Skinner JS, Wilmore JH,
Bouchard C. Effects of endurance exercise training on plasma HDL cholesterol levels depend on
levels of triglycerides: evidence from men of the Health, Risk Factors, Exercise Training and
Genetics (HERITAGE) Family Study. Arterioscler Thromb Vasc Biol. 2001 Jul;21(7):1226-32. PMID:
11451756 [PubMed - indexed for MEDLINE] <http://atvb.ahajournals.org/cgi/content/full/21/7/1226>

Annuzzi G, Jansson E, Kaijser L, Holmquist L, Carlson LA. Increased removal rate of exogenous
triglycerides after prolonged exercise in man: time course and effect of exercise duration.
Metabolism. 1987 May;36(5):438-43. <ncbi.nlm.nih.govquery.fcgiOpen ↗
PubMed&list_uids=3574133&dopt=Abstract>

Sady SP, Thompson PD, Cullinane EM, Kantor MA, Domagala E, Herbert PN. Prolonged exercise augments
plasma triglyceride clearance. JAMA. 1986 Nov 14;256(18):2552-5. <ncbi.nlm.nih.goventrOpen ↗
ez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3773156&dopt=Abstract>

Moreno LA, Quintela I, Fleta J, Sarria A, Roda L, Giner A, Bueno M. Postprandial triglyceridemia in
obese and non-obese adolescents. Importance of body composition and fat distribution. J Pediatr
Endocrinol Metab. 2001 Feb;14(2):193-202. <ncbi.nlm.nih.govquery.fcgiOpen ↗
eve&db=PubMed&list_uids=11305798&dopt=Abstract>

Mekki N, Christofilis MA, Charbonnier M, Atlan-Gepner C, Defoort C, Juhel C, Borel P, Portugal H,
Pauli AM, Vialettes B, Lairon D. Influence of obesity and body fat distribution on postprandial
lipemia and triglyceride-rich lipoproteins in adult women. J Clin Endocrinol Metab. 1999 Jan;84(1):184-
91. <http://jcem.endojournals.org/cgi/content/full/84/1/184>

Dhurandhar NV, Kulkarni PR. Serum cholesterol and triglyceride levels in weight reduction program
dropouts. Int J Food Sci Nutr. 1995 Feb;46(1):17-20. <ncbi.nlm.nih.govquery.fcgOpen ↗
i?cmd=Retrieve&db=PubMed&list_uids=7712338&dopt=Abstract>

Sonnichsen AC, Ritter MM, Mohrle W, Richter WO, Schwandt P. The waist-to-hip ratio corrected for
body mass index is related to serum triglycerides and high-density lipoprotein cholesterol but not
to parameters of glucose metabolism in healthy premenopausal women. <ncbi.nlm.nih.goveOpen ↗
ntrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8312684&dopt=Abstract>

Whitmore L, Trejos A, Mata L. Serum cholesterol, triglyceride, and high-density-lipoprotein
concentrations in men with different dietary and exercise regimens in Puriscal, Costa Rica. Arch
Latinoam Nutr. 1986 Jun;36(2):237-46. <ncbi.nlm.nih.govquery.fcgiOpen ↗
db=PubMed&list_uids=3632203&dopt=Abstract>

Chan DC, Watts GF, Mori TA, Barrett PH, Redgrave TG, Beilin LJ. Randomized controlled trial of the
effect of n-3 fatty acid supplementation on the metabolism of apolipoprotein B-100 and chylomicron
remnants in men with visceral obesity. Am J Clin Nutr. 2003 Feb;77(2):300-7. PMID: 12540386 [PubMed
- indexed for MEDLINE] <ncbi.nlm.nih.govquery.fcgiOpen ↗
uids=12540386&dopt=Abstract>

Jonkers IJ, Smelt AH, Ledeboer M, Hollum ME, Biemond I, Kuipers F, Stellaard F, Boverhof R,
Meinders AE, Lamers CH, Masclee AA. Gall bladder dysmotility: a risk factor for gall stone
formation in hypertriglyceridaemia and reversal on triglyceride lowering therapy by bezafibrate and
fish oil. Gut. 2003 Jan;52(1):109-15. PMID: 12477770 [PubMed - indexed for MEDLINE] <nc-nc-Open ↗
bi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12477770&dopt=Abstract>

Durrington PN, Bhatnagar D, Mackness MI, Morgan J, Julier K, Khan MA, France M. An omega-3
polyunsaturated fatty acid concentrate administered for one year decreased triglycerides in
simvastatin treated patients with coronary heart disease and persisting hypertriglyceridaemia.
Heart. 2001 May;85(5):544-8. PMID: 11303007 [PubMed - indexed for MEDLINE] <ncbi.nlm.ni-ncbi.nlm.ni-Open ↗
h.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11303007&dopt=Abstract>

Stark KD, Park EJ, Maines VA, Holub BJ. Effect of a fish-oil concentrate on serum lipids in
postmenopausal women receiving and not receiving hormone replacement therapy in a placebo-
controlled, double-blind trial. Am J Clin Nutr. 2000 Aug;72(2):389-94. PMID: 10919932 [PubMed -
indexed for MEDLINE] <http://www.ajcn.org/cgi/content/full/72/2/389>

Weber P, Raederstorff D. Triglyceride-lowering effect of omega-3 LC-polyunsaturated fatty acids--a
review. Nutr Metab Cardiovasc Dis. 2000 Feb;10(1):28-37. Review. PMID: 10812585 <ncbi.n-ncbi.n-Open ↗
lm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10812585&dopt=Abstract>

Harris WS. Nonpharmacologic treatment of hypertriglyceridemia: focus on fish oils. Clin Cardiol.
1999 Jun;22(6 Suppl):II40-3. Review. PMID: 10376196 [PubMed - indexed for MEDLINE] <ncb-ncb-Open ↗
i.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10376196&dopt=Abstract>

Marckmann P, Bladbjerg EM, Jespersen J. Dietary fish oil (4 g daily) and cardiovascular risk
markers in healthy men. Arterioscler Thromb Vasc Biol. 1997 Dec;17(12):3384-91. PMID: 9437183
[PubMed - indexed for MEDLINE] <ncbi.nlm.nih.govquery.fcgiOpen ↗
ed&list_uids=9437183&dopt=Abstract>

Roche HM, Gibney MJ. Postprandial triacylglycerolaemia: the effect of low-fat dietary treatment
with and without fish oil supplementation. Eur J Clin Nutr. 1996 Sep;50(9):617-24. PMID: 8880041
[PubMed - indexed for MEDLINE] <ncbi.nlm.nih.govquery.fcgiOpen ↗
ed&list_uids=8880041&dopt=Abstract>

Mori TA, Vandongen R, Beilin LJ, Burke V, Morris J, Ritchie J. Effects of varying dietary fat,
fish, and fish oils on blood lipids in a randomized controlled trial in men at risk of heart
disease. Am J Clin Nutr. 1994 May;59(5):1060-8. PMID: 8172092 [PubMed - indexed for MEDLINE] <http-
://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8172092&dopt=Abstract>

Tato F, Keller C, Wolfram G. Effects of fish oil concentrate on lipoproteins and apolipoproteins in
familial combined hyperlipidemia. Clin Investig. 1993 Apr;71(4):314-8. PMID: 8471818 [PubMed -
indexed for MEDLINE] <ncbi.nlm.nih.govquery.fcgiOpen ↗
ds=8471818&dopt=Abstract>

Zakaria B, Bertsch S. [Low-dose omega-3 fatty acids as lipid lowering agents in the practice. A
field study of ambulatory patients in general practice] Fortschr Med. 1992 Apr 10;110(10):178-82.
German. PMID: 1577358 [PubMed - indexed for MEDLINE] <ncbi.nlm.nih.govquery.fcgOpen ↗
i?cmd=Retrieve&db=PubMed&list_uids=1577358&dopt=Abstract>

Bairati I, Roy L, Meyer F. Effects of a fish oil supplement on blood pressure and serum lipids in
patients treated for coronary artery disease. Can J Cardiol. 1992 Jan-Feb;8(1):41-6. PMID: 1617510
[PubMed - indexed for MEDLINE] <ncbi.nlm.nih.govquery.fcgiOpen ↗
ed&list_uids=1617510&dopt=Abstract>

Burr ML. Fish food, fish oil and cardiovascular disease. Clin Exp Hypertens A. 1992;14(1-2):181-92.
Review. PMID: 1541036 [PubMed - indexed for MEDLINE] <ncbi.nlm.nih.govquery.fcgOpen ↗
i?cmd=Retrieve&db=PubMed&list_uids=1541036&dopt=Abstract>

Deslypere JP. Influence of supplementation with N-3 fatty acids on different coronary risk factors
in men--a placebo controlled study. Verh K Acad Geneeskd Belg. 1992;54(3):189-216. PMID: 1413984
[PubMed - indexed for MEDLINE] <ncbi.nlm.nih.govquery.fcgiOpen ↗
ed&list_uids=1413984&dopt=Abstract>

Harris WS, Windsor SL, Dujovne CA. Effects of four doses of n-3 fatty acids given to hyperlipidemic
patients for six months. J Am Coll Nutr. 1991 Jun;10(3):220-7. PMID: 1832701 [PubMed - indexed for
MEDLINE] <ncbi.nlm.nih.govquery.fcgiOpen ↗
opt=Abstract>

Terres W, Beil U, Reimann B, Tiede S, Bleifeld W. [Low-dose fish oil in primary
hypertriglyceridemia. A randomized placebo-controlled study] Z Kardiol. 1991 Jan;80(1):20-4.
German. PMID: 2035283 [PubMed - indexed for MEDLINE] <ncbi.nlm.nih.govquery.fcgOpen ↗
i?cmd=Retrieve&db=PubMed&list_uids=2035283&dopt=Abstract>

DeLany JP, Vivian VM, Snook JT, Anderson PA. Effects of fish oil on serum lipids in men during a
controlled feeding trial. Am J Clin Nutr. 1990 Sep;52(3):477-85. PMID: 2203252 [PubMed - indexed
for MEDLINE] <ncbi.nlm.nih.govquery.fcgiOpen ↗
52&dopt=Abstract>

Bohn KA, Friisk CF, Boe OW, Hysing J. [Effect on the lipid profile of diet supplemented with fish
oil concentrate] Tidsskr Nor Laegeforen. 1990 May 20;110(13):1693-6. Norwegian. PMID: 2195704
[PubMed - indexed for MEDLINE] <ncbi.nlm.nih.govquery.fcgiOpen ↗
ed&list_uids=2195704&dopt=Abstract>

Radack KL, Deck CC, Huster GA. n-3 fatty acid effects on lipids, lipoproteins, and apolipoproteins
at very low doses: results of a randomized controlled trial in hypertriglyceridemic subjects. Am J
Clin Nutr. 1990 Apr;51(4):599-605. PMID: 2181859 [PubMed - indexed for MEDLINE] <ncbi.n-ncbi.n-Open ↗
lm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2181859&dopt=Abstract>

Bhathena SJ, Ali AA, Haudenschild C, Latham P, Ranich T, Mohamed AI, Hansen CT, Velasquez MT.
Dietary Flaxseed Meal is More Protective Than Soy Protein Concentrate Against Hypertriglyceridemia
and Steatosis of the Liver in an Animal Model of Obesity. J Am Coll Nutr. 2003 Apr;22(2):157-64.
PMID: 12672712 [PubMed - in process] <ncbi.nlm.nih.govquery.fcgiOpen ↗
b=PubMed&list_uids=12672712&dopt=Abstract

Robert Kershaw <[email hidden]> wrote in part:

Quoted message said:

I have access top pubmed and all the other data baes, despite this all I can get is the abstract to
all of these articles. How do I get a PDF of the article from pubmed or medline?

Thank You, Robert Kershaw

In most cases, you need to subscribe to each journal or pay a per-article fee at each website. Some
journals make older papers available on the web at no cost.

What I do is go to the library. For recent papers in less-accessible journals I write to the author
and request a copy.
--
Jim Chinnis Warrenton, Virginia, USA

Piantanida Equine Services said:

I also had problems with my cholesterol & Triglycerides My Doctor has me on 80 mg lipitor also
recently added a drug called zitia for my cholesterol.The numbers are good. For my Triglycerides
he has me on a drug called Lopid, I take 600 mg twice a day. This seems to do a good job. Check
with your Cardiologist or Primary about this drug .

There is a potentially lethal interaction between Lipitor and Lopid.

It would be my suggestion that you bring this up with your doctor today if this has not been
discussed.

Truthfully,

Andrew

--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
heartmdphd.comheartmdphd.comOpen ↗

"Dr. Andrew B. Chung, MD/PhD" <[email hidden]> wrote in message
"]news:[email hidden]...
: Piantanida Equine Services wrote:
:
: > I also had problems with my cholesterol & Triglycerides My Doctor has me on 80 mg lipitor also
: > recently added a drug called
zitia
: > for my cholesterol.The numbers are good. For my Triglycerides he has me
on a
: > drug called Lopid, I take 600 mg twice a day. This seems to do a good
job.
: > Check with your Cardiologist or Primary about this drug .
:
: There is a potentially lethal interaction between Lipitor and Lopid.
:
: It would be my suggestion that you bring this up with your doctor today if
this
: has not been discussed.
:
a potentially lethal interaction between all statins or just lipitor?

noway,

You should also be concerned about metabolic syndrome. You have at least two signs are low hdl and
high trig. You need one confirming sign from the following: high bp, central obesity, high fasting
plasma blood glucose. See this from the Cleveland Clinic for more details: clevelandclinic.orghealthOpen ↗
info/docs/3000/3057.asp?index=10783

[email hidden] wrote in message news:<[email hidden]>...

Quoted message said:

My latest lipid profile (12 hour fast) included:

Total Cholesterol 185 HDL Cholesterol 40 Triglycerides 411

What concerns me most about these readings is the high triglyceride count. Is there a statin, or
some other medication, that would lower triglycerides to somewhere below 200?

Thanks,

"Jim Horne" <[email hidden]> wrote in message news:<[email hidden]>...

Quoted message said:

"Dr. Andrew B. Chung, MD/PhD" <[email hidden]> wrote in message
"]news:[email hidden]...
: Piantanida Equine Services wrote:
:
: > I also had problems with my cholesterol & Triglycerides My Doctor has me on 80 mg lipitor also
: > recently added a drug called
zitia
: > for my cholesterol.The numbers are good. For my Triglycerides he has me
on a
: > drug called Lopid, I take 600 mg twice a day. This seems to do a good
job.
: > Check with your Cardiologist or Primary about this drug .
:
: There is a potentially lethal interaction between Lipitor and Lopid.
:
: It would be my suggestion that you bring this up with your doctor today if
this
: has not been discussed.
:
a potentially lethal interaction between all statins or just lipitor?

Between gemfibrozil and all statins.

Humbly,

Andrew

--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
heartmdphd.comheartmdphd.comOpen ↗

"Dr. Andrew B. Chung, MD/PhD" <[email hidden]> wrote in message
"]news:[email hidden]...
: "Jim Horne" <[email hidden]> wrote in message
news:<[email hidden]>...
: > "Dr. Andrew B. Chung, MD/PhD" <[email hidden]> wrote in message
: > "]news:[email hidden]...
: > : Piantanida Equine Services wrote:
: > :
: > : > I also had problems with my cholesterol & Triglycerides My Doctor has me on 80 mg lipitor
: > : > also recently added a drug called
: > zitia
: > : > for my cholesterol.The numbers are good. For my Triglycerides he has
me
: > on a
: > : > drug called Lopid, I take 600 mg twice a day. This seems to do a
good
: > job.
: > : > Check with your Cardiologist or Primary about this drug .
: > :
: > : There is a potentially lethal interaction between Lipitor and Lopid.
: > :
: > : It would be my suggestion that you bring this up with your doctor
today if
: > this
: > : has not been discussed.
: > :
: > a potentially lethal interaction between all statins or just lipitor?
:
: Between gemfibrozil and all statins.
:

it appears cerivastatin (Baycol) was more concerning relative to rhabdomyolysis than other statins.
Baycol was removed from the market in mid 2001.

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