Re: Statin-induced CoQ10 depletion~the unfolding of the greatest medical tragedy of all time



A

Anth

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http://www.drugintel.com/drugs/statins/Langsjoen.pdf
Here's the version with references....
Anth

"rb" <[email protected]> wrote in message
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> STATIN-INDUCED CARDIOMYOPATHY
>
> INTRODUCTION TO THE CITIZEN'S PETITION ON STATINS
>
> By Peter H. Langsjoen, MD
>
> The medical profession has, after more than 30 years of excellent
> propaganda, successfully created the wholly iatrogenic - "pseudo-disease"
> dubbed "hypercholesterolemia" and the associated malady "cholesterol
> neurosis". After decades of dismal failure to cure this "disease" of

numbers
> with low fat diets and a host of cholesterol lowering drugs, the medical
> profession stumbled upon the magic bullet, the cure for this dreaded
> artificial disease - statins (HMG-CoA reductase inhibitors). First

released
> on the US market in 1987, statins have rapidly grown into one of the most
> widely prescribed class of drugs in history. Statins do three things:
>
> 1. They block the body's ability to make cholesterol, thus lowering the
> blood level of cholesterol, thereby curing cholesterol neurosis. Doctors

and
> patients equally neurotic have immediate gratification. The "evil" high
> cholesterol has been dramatically lowered and the future is bright and
> promising. So far...so good.
>
> 2. Unrelated to their cholesterol lowering, statins have been found to

have
> anti-inflammatory, plaque-stabilizing properties which have a slight

benefit
> in coronary heart disease.
>
> 3. Statins kill people - lots of people - and they wound many, many more.
> All patients taking statins become depleted in Coenzyme Q10 (CoQ10),
> eventually - those patients who start with a relatively low CoQ10 levels
> (the elderly and patients with heart failure) begin to manifest
> signs/symptoms of CoQ10 deficiency relatively rapidly - in 6 to 12 months.
> Younger, healthier people who's only "illness" is the non-illness
> "hypercholesterolemia" can tolerate statins for several years before

getting
> into trouble with fatigue, muscle weakness and soreness (usually with

normal
> muscle enzyme CPK tests) and most ominously - heart failure.
>
> In my practice of 17 years in Tyler, Texas, I have seen a frightening
> increase in heart failure secondary to statin usage, "statin
> cardiomyopathy". Over the past five years, statins have become more

potent,
> are being prescribed in higher doses, and are being used with reckless
> abandon in the elderly and in patients with "normal" cholesterol levels.

We
> are in the midst of a CHF epidemic in the US with a dramatic increase over
> the past decade. Are we causing this epidemic through our zealous use of
> statins? In large part I think the answer is yes. We are now in a position
> to witness the unfolding of the greatest medical tragedy of all time -

never
> before in history has the medical establishment knowingly (Merck & Co.,

Inc.
> has two 1990 patents combining CoQ10 with statins to prevent CoQ10

depletion
> and attendant side effects) created a life threatening nutrient deficiency
> in millions of otherwise healthy people, only to then sit back with
> arrogance and horrific irresponsibility and watch to see what happens - as

I
> see two to three new statin cardiomyopathies per week in my practice, I
> cannot help but view my once great profession with a mixture of sorrow and
> contempt.
>
> Statin-induced CoQ10 depletion is the topic of a recent petition to the

FDA
> requesting that this drug/nutrient interaction be identified in a black

box
> warning as part of statin package insert information. A comprehensive

review
> of animal and human trials addressing this issue has been submitted to the
> FDA as a supporting document. We, of course, do not expect any response

from
> the FDA, but 10 years from now when the full extent of statin toxicity
> becomes painfully evident, at least we can, in good conscience, know that

we
> tried and who knows, sometimes small sparks may spread in dry grass.
>
>
>
> See Also:
>
> Cholesterol Drugs And The Depletion Of Coenzyme Q10: A Review Of Human And
> Animal Data.
> By Peter H. Langsjoen, MD
>
> Citizen Petition: Needed - A Change In The Labeling Of All Statin Drugs
>
>