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Clin Chim Acta. 2004 Mar;341(1-2):165-72. Related Articles, Links
Blood lactoferrin release induced by running exercise in normal volunteers: antibacterial activity.
Inoue H, Sakai M, Kaida Y, Kaibara K.
Radioisotopes Institute for Basic and Clinical Medicine, Kurume University School of Medicine, 67
Asahi-machi, Kurume 830-0011, Japan.
Background: The aim of this study was to determine serum lactoferrin concentrations and serum
antibacterial activity before and after running exercise. Methods: Twenty-four healthy young men
were randomly assigned to high, middle, or low intensity of exercise groups (5000 steps running at
180, 130, and 80 steps/min, respectively). Blood samples were collected at baseline and immediately,
1 and 4 h after exercise. Concentrations of circulating neutrophils, serum lactoferrin, iron in
whole blood, and serum iron were measured. Antibacterial activity of serum was evaluated using live
Micrococcus luteus. Results: The numbers of circulating neutrophils were increased by 20.0% and
15.5% 1 h after exercise in high and middle groups (both P<0.01), respectively. Serum lactoferrin
concentrations were significantly increased immediately after exercise by 48.3% and 33.0% in the
high and middle groups (both P<0.01), respectively. No significant changes in total iron or serum
iron concentrations were observed during the study. Antibacterial activities of serum collected
immediately after exercise in the high and middle groups were significantly stronger than those
before exercise, by 31.2% and 25.4% (both P<0.05), respectively. Conclusions: Serum lactoferrin
concentrations are increased immediately after running exercise and may play an antibacterial role
in host defenses before mobilization of neutrophils into the circulating pool.
PMID: 14967173 [PubMed - in process]
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http://pages.ivillage.com/ironjustice/manisaherbivore DEAD PEOPLE WALKING
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Blood lactoferrin release induced by running exercise in normal volunteers: antibacterial activity.
Inoue H, Sakai M, Kaida Y, Kaibara K.
Radioisotopes Institute for Basic and Clinical Medicine, Kurume University School of Medicine, 67
Asahi-machi, Kurume 830-0011, Japan.
Background: The aim of this study was to determine serum lactoferrin concentrations and serum
antibacterial activity before and after running exercise. Methods: Twenty-four healthy young men
were randomly assigned to high, middle, or low intensity of exercise groups (5000 steps running at
180, 130, and 80 steps/min, respectively). Blood samples were collected at baseline and immediately,
1 and 4 h after exercise. Concentrations of circulating neutrophils, serum lactoferrin, iron in
whole blood, and serum iron were measured. Antibacterial activity of serum was evaluated using live
Micrococcus luteus. Results: The numbers of circulating neutrophils were increased by 20.0% and
15.5% 1 h after exercise in high and middle groups (both P<0.01), respectively. Serum lactoferrin
concentrations were significantly increased immediately after exercise by 48.3% and 33.0% in the
high and middle groups (both P<0.01), respectively. No significant changes in total iron or serum
iron concentrations were observed during the study. Antibacterial activities of serum collected
immediately after exercise in the high and middle groups were significantly stronger than those
before exercise, by 31.2% and 25.4% (both P<0.05), respectively. Conclusions: Serum lactoferrin
concentrations are increased immediately after running exercise and may play an antibacterial role
in host defenses before mobilization of neutrophils into the circulating pool.
PMID: 14967173 [PubMed - in process]
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------
Who loves ya. Tom Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com Man Is A Herbivore!
http://pages.ivillage.com/ironjustice/manisaherbivore DEAD PEOPLE WALKING
http://pages.ivillage.com/ironjustice/deadpeoplewalking