"Sbharris[atsign]ix.netcom.com" <[email hidden]> wrote in message
news:[email hidden]...
Quoted message said:George Cherry said:Perhaps their diets do not provide the minerals
and vitamins which are conducive to equanimity?
GWC
1: J Child Adolesc Psychopharmacol. 2002 Fall;12(3):205-19. Related
Articles, Links
Treatment of mood lability and explosive rage with minerals and vitamins:
two case studies in children.
Kaplan BJ, Crawford SG, Gardner B, Farrelly G.
Department of Paediatrics, University of Calgary, Calgary, Alberta,
Canada.
[email hidden]
A micronutrient supplement containing a broad range of dietary minerals
and
vitamins is being examined for the treatment of mood lability in both
adults
and children (Kaplan et al. 2001; Popper 2001). During pilot work, two
medication-free boys with mood lability and explosive rage were studied
in
an open-label treatment followed by reversal and retreatment. One child
was
an 8-year-old with atypical obsessive-compulsive disorder, and the other
was
a 12-year-old with pervasive developmental delay. Both boys were
monitored
using the mood and temper items from the Conners Parent Rating Scale, as
well as the Child Behavior Checklist. In addition, the boy with atypical
obsessive-compulsive disorder was monitored with the child version of the
Yale-Brown Obsessive Compulsive Scale. Both boys benefited from the
micronutrient supplement when examined in ABAB designs: mood, angry
outbursts, and obsessional symptoms improved when initially treated,
returned when not taking the supplement, and remitted when the
micronutrient
supplement was reintroduced. Both boys have been followed and are stable
on
the nutritional supplement for over 2 years. These cases suggest that
mood
lability and explosive rage can, in some cases, be managed with a mixture
of
biologically active minerals and vitamins, without using lithium or other
traditional psychopharmacologic agents.
Publication Types:
a.. Case Reports
PMID: 12427294 [PubMed - indexed for MEDLINE]
COMMENT:
I don't know, George, but I think I'd be mightily embarrassed to
published a 2-person open-label study of a simple supplement that could
just as easily be blinded and placebo controlled in at least a handful
of people.
I had hoped my post would drive my "meat-eaters growl"
point home by provoking vivid illustrative outbursts
of violent rage. I also thought it was funny to compare
the growling and yelling here to an "8-year-old with
atypical obsessive-compulsive disorder, and ... a
12-year-old with pervasive developmental delay."
Alas, all I got was this cool reasoned intellectual
response from our resident Allopathic Ace.
Quoted message said:There is rationale for reporting "case reports" in a few
people (or even one) when the disease is rare or EXTREMELY nasty,
Alas, "explosive rage" is anything but rare here.
Quoted message said:or
the treatment is long or nasty, and/or is impossible to blind, or
blinding it makes no sense (e.g.: two well documented patients with a
historcally uniformly fatal cancer, heroically treated, who were
completely unexpectedly cured as of five years from treatment.) But
the kind of short thing with the supplements above, where placebo
effects are expected to be extreme, and the N is 2, is academic
padding.
Not gold standard, huh? : o ) Where's the "explosive rage", dammit?
Seriously, the attention to the kids alone will improve them. The placebo
effect of attention is probably greater than the placebo effect of the
pills.
Quoted message said:It's worse than no publication at all as far as the scientific
community is concerned. It helps only as means to add to the author's
CV for promotion purposes, where promotion committees measure such junk
by the column-inch. Grrrr.
Yep, as a former denizen of Academe, I can tell
you that the number of citations count. But something
else I can tell you is this: faculties, when voting on tenure,
do have their bull-[censored] detectors on. They really, in
general, don't want to be associated with charlatans.
George
