Depends on the design of the seatpost and whether you'll be able to adjust the seat angle properly for a flat seat once it's turned around. And if you currently have a seatpost with set back and you turn it around you'll have a fast forward style post that steepens the effective seat tube angle, not a zero offset post. That could be useful if you're fitting a road bike with aero bars for triathlons or TTs.
But it's easy enough to swivel the post around, remount the seat to see if you can still adjust it's angle properly and see where it places your seat.
Good luck,
-Dave