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SSRIs & Bufotoxin

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01 / Original postSSRIs & BufotoxinNathan · 8 May 2004 02 / This pagePosts 1–6Page 1 of 1 · chronological order 03 / Latest replyPost #6David Wright · 8 May 2004

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General fitness, health and nutrition
Published
8 May 2004
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8 May 2004
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Nathan
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  1. Original post
    Nathan
    Archived post
    #1

    I heard that neurotoxic effects can be caused by the
    consumption of SSRI drugs. As it was explained to me, the
    serotonin reuptake pump is inhibited, therefore serotonin
    remains in the synapse for a longer period of time. While in
    the synapse, it begins to breakdown. One of the metabolites
    of serotonin (while not being broken down by MAO), I was
    told, is BUFOTOXIN. This will destroy the neurons on either
    side of the synapse.

    Is there any truth to this, or am I being fed something
    totally made up? I did a google search for SSRI BUFOTOXIN,
    however, the only search result was a dead end. Searches for
    the toxic effects for SSRI drugs made no mention of
    Bufotoxin. This leads me to believe the bufotoxin story is
    false, however it never hurts to explore these things
    further (and no, I am not taking any SSRIs).

    Regards, Nathan.

    Report
  2. Tpfkaa
    Archived post
    #2
    (nathan) said:

    I heard that neurotoxic effects can be caused by the
    consumption of SSRI drugs. As it was explained to me, the
    serotonin reuptake pump is inhibited, therefore serotonin
    remains in the synapse for a longer period of time. While
    in the synapse, it begins to breakdown. One of the
    metabolites of serotonin (while not being broken down by
    MAO), I was told, is BUFOTOXIN. This will destroy the
    neurons on either side of the synapse.

    Never heard of it. I suspect the report you're referring
    to is bogus.

    Report
  3. Tpfkaa
    Archived post
    #3
    TPFKAA said:

    On 2004-05-03 10:27:29 -0400, [email hidden]

    (nathan) said:

    I heard that neurotoxic effects can be caused by the
    consumption of SSRI drugs. As it was explained to me, the
    serotonin reuptake pump is inhibited, therefore serotonin
    remains in the synapse for a longer period of time. While
    in the synapse, it begins to breakdown. One of the
    metabolites of serotonin (while not being broken down by
    MAO), I was told, is BUFOTOXIN. This will destroy the
    neurons on either side of the synapse.

    Never heard of it. I suspect the report you're referring
    to is bogus.

    Actually, isn't bufotoxin the stuff produced by those
    "poison dart" frogs? At least, it's something that sounds
    like that. Doubt it's related to SSRIs, at any rate.

    Report
  4. David Wright
    Archived post
    #4

    In article <2004050319244716807%tpfkaa@anoncom>,

    TPFKAA said:
    TPFKAA said:

    On 2004-05-03 10:27:29 -0400, [email hidden]

    (nathan) said:

    I heard that neurotoxic effects can be caused by the
    consumption of SSRI drugs. As it was explained to me,
    the serotonin reuptake pump is inhibited, therefore
    serotonin remains in the synapse for a longer period of
    time. While in the synapse, it begins to breakdown. One
    of the metabolites of serotonin (while not being broken
    down by MAO), I was told, is BUFOTOXIN. This will
    destroy the neurons on either side of the synapse.

    Never heard of it. I suspect the report you're referring
    to is bogus.

    Actually, isn't bufotoxin the stuff produced by those
    "poison dart" frogs? At least, it's something that sounds
    like that. Doubt it's related to SSRIs, at any rate.

    Toads, not frogs. I think it's that stuff on the toads that
    people were licking to try to get high.

    -- David Wright :: alphabeta at prodigy.net These are my
    opinions only, but they're almost always correct. "If I
    have not seen as far as others, it is because giants were
    standing on my shoulders." (Hal Abelson, MIT)

    Report
  5. Fifty Hertz
    Archived post
    #5
    Quoted message said:
    Quoted message said:

    Actually, isn't bufotoxin the stuff produced by those
    "poison dart" frogs?

    Quoted message said:

    Toads, not frogs. I think it's that stuff on the toads
    that people were licking to try to get high.

    Dart frogs are South American tiny highly coloured
    frogs. Quite poisonous. Not the psychedelic toads to
    which you refer.

    Report
  6. David Wright
    Archived post
    #6

    In article <[email hidden]>,

    Fifty Hertz upturned(NoSpAm)@hotmail.com said:
    Quoted message said:
    Quoted message said:

    Actually, isn't bufotoxin the stuff produced by those
    "poison dart" frogs?

    Quoted message said:

    Toads, not frogs. I think it's that stuff on the toads
    that people were licking to try to get high.

    Dart frogs are South American tiny highly coloured
    frogs. Quite poisonous. Not the psychedelic toads to
    which you refer.

    Yes, I know. I shouldn't have been so terse. The toad in
    question is Bufo gargarizans and has nothing to do with
    poison dart frogs. Licking one of *those* would probably be
    your last act on earth.

    -- David Wright :: alphabeta at prodigy.net These are my
    opinions only, but they're almost always correct. "If I
    have not seen as far as others, it is because giants were
    standing on my shoulders." (Hal Abelson, MIT)

    Report

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