Quoted post said:Originally Posted by paulambry
Quoted post said:Originally Posted by matagi
Quoted post said:Originally Posted by paulambry
Ma, do you have a view on this?
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Statins benefit a select group of people, but there are a lot of people who are on them who really should not be. These things have some potentially horrendous side effects, so a doctor should not be starting a patient on them just because they have a high cholesterol - they need to look at their risk factor profile and that that into consideration too. You treat the person not the number, but unfortunately a lot of doctors fail to do that.
Every time I read the "if people stop taking these drugs they will die" line the Heart Foundation seems to want to peddle, I want to punch someone in the face. What a load of emotive [censored].
So Ma, have we established a causal link between high cholesterol and heart disease? Or is it a circumstantial / statistical / epidemiological link?
I can never seem to get a definitive answer on this stuff.
Well that's because there isn't really a definitive answer. There is an association, but the problem is that cholesterol per se is not the culprit. As with all things pertaining to the human body, the problem is multifactorial. There is evidence now suggesting inflammation has a far greater role - we even measure CRP (which is an inflammatory marker) as part of the stratification of risk.
As for "good" cholesterol vs "bad" cholesterol - the idiot that coined those terms should be shot. LDL cholesterol (or "bad" cholesterol) is manufactured by the human body. It's function is to deliver cholesterol to cells (and cells need cholesterol to keep their cell membranes fluid) so it is in fact essential. People are now starting to look at the glycation of lipoproteins as the culprit in atherosclerosis (even though this is not a new concept), which certainly has more merit than leaping up and down loudly proclaiming we should all be reducing our cholesterol levels below a certain magic number or we will all turn into solid blocks of atheroma.